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由全科医生护理的2型糖尿病患者队列中血糖长期控制及性能指标的变化:“摩德纳糖尿病项目”的研究结果

Changes in long-term glycemic control and performance indicators in a cohort of type 2 diabetic patients cared for by general practitioners: findings from the "Modena Diabetes Project".

作者信息

Ciardullo A V, Daghio M M, Brunetti M, Bevini M, Daya G, Feltri G, Novi D, Goldoni C A, Messori A, Guerzoni A, Magrini N

机构信息

Centre for the Evaluation of the Effectiveness of Health Care, CeVEAS, Azienda USL, Modena, Italy.

出版信息

Nutr Metab Cardiovasc Dis. 2003 Dec;13(6):372-6. doi: 10.1016/s0939-4753(03)80006-6.

Abstract

BACKGROUND AND AIM

General practitioners (GPs) are being increasingly asked to play a key role in the shared care of people with diabetes mellitus, but data concerning the effects of this in Italy are still scarce. We therefore evaluated the 4-year follow-up changes in outcomes and performance indicators in type 2 diabetic patients cared for by GPs in the framework of the "Modena Diabetes Project".

METHODS AND RESULTS

Seventy-four percent of the local GPs participating in the project (387 out of 521) sent 5260 paired baseline and follow-up datasheets. The baseline characteristics of the type 2 diabetic patients (49.6% male) were a mean age of 67.3+/-11.2 years, a mean disease duration of 10.9+/-7.4 years, a mean BMI of 28.7+/-4.8 kg/m2, and a mean HbA1c level 7.56+/-1.52%. After four years follow-up, the individual before/after match-paired outcomes revealed an improvement in glycemic control: HbA1c levels significantly decreased to 7.39+/-1.31%, and the percentage of patients with HbA1c level of <6.5% significantly increased from 15.7% to 22.1%. There was also a significant decrease in body weight (from 78.3+/-14.8 to 77.6+/-14.6 kg) and BMI (from 28.8+/-4.8 to 28.5+/-4.9 kg/m2). The time trends of glycemic control significantly improved during the 4-year follow up, but those of the body weight and BMI values did not. Furthermore, the percentages of performance indicators matching the expected rate of recurrence per each year of follow-up significantly improved during the study period.

CONCLUSIONS

Long-term glycemic control and the performance indicators relating to the type 2 diabetic patients participating in our shared care programme progressively improved.

摘要

背景与目的

越来越多的人要求全科医生(GPs)在糖尿病患者的共同照护中发挥关键作用,但在意大利,关于其效果的数据仍然很少。因此,我们在“摩德纳糖尿病项目”的框架内,评估了由全科医生照护的2型糖尿病患者4年随访期间的结局和绩效指标变化。

方法与结果

参与该项目的当地全科医生中有74%(521名中的387名)发送了5260份配对的基线和随访数据表。2型糖尿病患者(男性占49.6%)的基线特征为平均年龄67.3±11.2岁,平均病程10.9±7.4年,平均体重指数28.7±4.8kg/m²,平均糖化血红蛋白水平7.56±1.52%。经过四年随访,个体前后匹配配对的结局显示血糖控制有所改善:糖化血红蛋白水平显著降至7.39±1.31%,糖化血红蛋白水平<6.5%的患者百分比从15.7%显著增加至22.1%。体重(从78.3±14.8降至77.6±14.6kg)和体重指数(从28.8±4.8降至28.5±4.9kg/m²)也显著下降。血糖控制的时间趋势在4年随访期间显著改善,但体重和体重指数值的时间趋势没有改善。此外,在研究期间,与每年随访预期复发率匹配的绩效指标百分比显著提高。

结论

参与我们共同照护项目的2型糖尿病患者的长期血糖控制和绩效指标逐渐改善。

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