Srouji I A, Resouly A, Cree I A
Department of Otolaryngology, Queen Alexandra Hospital, Portsmouth, UK.
J Laryngol Otol. 2004 Feb;118(2):162-4. doi: 10.1258/002221504772784685.
Parathyroid carcinoma is a rare tumour, which is often difficult to diagnose. This is especially true in patients with pre-existing tertiary hyperparathyroidism of end-stage renal disease. A case is presented of parathyroid carcinoma in a haemodialysis patient with unusual thymic involvement. After demonstrating the difficulty in pre-operative diagnosis and risk of recurrence, the importance of non-surgical treatment options is discussed and the investigation of individual tumour chemosensitivity is introduced, which is new to this type of cancer.
甲状旁腺癌是一种罕见的肿瘤,通常难以诊断。对于已有终末期肾病所致三发性甲状旁腺功能亢进的患者而言尤其如此。本文介绍了一例血液透析患者发生甲状旁腺癌并伴有罕见胸腺受累的病例。在阐述了术前诊断的困难及复发风险后,讨论了非手术治疗方案的重要性,并介绍了针对个体肿瘤化学敏感性的研究,这在这类癌症中尚属首次。