Lee Tsung-Chieh, Huang Ke-Feng, Hsiao Ming-Liang, Tang Shih-Tsang, Young Sheunn-Tsong
Institute of Biomedical Engineering of National Yang-Ming University, Taipei, Taiwan, ROC.
Comput Methods Programs Biomed. 2004 Mar;73(3):209-19. doi: 10.1016/S0169-2607(03)00067-1.
Numerous electrical analog models of the circulatory system have been proposed. However, conventional models are either too simple, focusing exclusively on heart function, or overly complex, characterizing arteries in excessive detail. The vessel beds, which comprise arteries, capillaries and veins, are well known to be responsible for most of the pressure drop in blood pressure and to dominate the draining of blood flow. Consequently, electrical analog models of the circulatory system should pay more attention to the vessel beds. This investigation divided the arterial system into several aortic segments with vessel beds, and proposed a model that used electrical lumped elements to represent the vessel beds. The model was adopted to simulate blood pressure propagation by considering each vessel bed as an isolated subsystem. The transfer function between the terminals of isolated subsystems was used to identify the electrical components of the lumped elements that characterized the vessel beds. Simulation results reveal that the compliance and impedance of the vessel beds are larger than in previous models that focused on the aorta or arteries. The proposed electrical lumped model could deal with much more information than the simple models due to the lumped element structure. Furthermore, its isolated subsystem approach also makes the proposed model significantly easier to use than the complex models.
人们已经提出了许多循环系统的电学模拟模型。然而,传统模型要么过于简单,仅专注于心脏功能,要么过于复杂,对动脉的描述过于详细。众所周知,由动脉、毛细血管和静脉组成的血管床是造成大部分血压压降的原因,并且在血流引流中占主导地位。因此,循环系统的电学模拟模型应更多地关注血管床。本研究将动脉系统划分为几个带有血管床的主动脉段,并提出了一个使用集总元件来表示血管床的模型。该模型通过将每个血管床视为一个独立子系统来模拟血压传播。孤立子系统终端之间的传递函数用于识别表征血管床的集总元件的电气组件。模拟结果表明,与之前专注于主动脉或动脉的模型相比,血管床的顺应性和阻抗更大。由于集总元件结构,所提出的集总电学模型能够处理比简单模型更多的信息。此外,其孤立子系统方法也使得所提出的模型比复杂模型更易于使用。