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对苯二酚,一种蔗糖诱导的变形链球菌凝集和黏附的控制剂。

Hydroquinone, a control agent of agglutination and adherence of Streptococcus mutans induced by sucrose.

作者信息

Himejima Masaki, Nihei Ken-ichi, Kubo Isao

机构信息

Department of Environmental Science, Policy and Management, University of California, Berkeley, CA 94720-3112, USA.

出版信息

Bioorg Med Chem. 2004 Mar 1;12(5):921-5. doi: 10.1016/j.bmc.2003.12.020.

DOI:10.1016/j.bmc.2003.12.020
PMID:14980604
Abstract

Hydroquinone was found to alter agglutination of Streptococcus mutans induced by sucrose. The newly formed agglutination product produced by hydroquinone does not kill this cariogenic bacterium and the formation is reversible. The agglutination altering activity of hydroquinone seems to be specific for strains of S. mutans. As a result, hydroquinone inhibits sucrose-induced adherence of S. mutans.

摘要

对苯二酚被发现可改变蔗糖诱导的变形链球菌的凝集作用。对苯二酚产生的新形成的凝集产物不会杀死这种致龋细菌,并且这种形成是可逆的。对苯二酚的凝集改变活性似乎对变形链球菌菌株具有特异性。因此,对苯二酚可抑制蔗糖诱导的变形链球菌的黏附。

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