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[金氏金杆菌与儿童骨关节炎感染]

[Kingella kingae and osteoarticular infections in children].

作者信息

Nordal Ellen, Olausson Sofia, Hvidsten Dag, Klingenberg Claus

机构信息

Barneavdelingen, Universitetssykehuset Nord-Norge, 9038 Tromsø.

出版信息

Tidsskr Nor Laegeforen. 2004 Feb 19;124(4):492-3.

Abstract

BACKGROUND

In septic arthritis and osteomyelitis in children, the infectious agent is frequently not identified because of failure in obtaining bacterial growth from blood culture or osteoarticular aspirations.

MATERIAL AND METHODS

We report a case of septic arthritis caused by Kingella kingae in a two-year-old boy. On the basis of a PubMed literature search, we present an overview of osteoarticular infections with K kingae in childhood.

RESULTS AND INTERPRETATION

Over the last ten years there has been an increasing number of reports on osteoarticular infection in children caused by K kingae. The clinical course is usually benign. Direct inoculation of osteoarticular specimens into blood culture bottles is important in order to enhance isolation of K kingae, as this organism will often fail to grow when plated directly on solid media. Improved culture methods and increased awareness are important in order to identify the organism and thus enable targeted antibiotic therapy.

摘要

背景

在儿童脓毒性关节炎和骨髓炎中,由于从血培养或骨关节穿刺液中未能获得细菌生长,感染病原体常常无法确定。

材料与方法

我们报告了一例由金氏金杆菌引起的两岁男孩脓毒性关节炎病例。基于PubMed文献检索,我们概述了儿童金氏金杆菌骨关节感染情况。

结果与解读

在过去十年中,关于金氏金杆菌引起儿童骨关节感染的报道越来越多。临床病程通常为良性。将骨关节标本直接接种到血培养瓶中对于提高金氏金杆菌的分离率很重要,因为这种微生物直接接种在固体培养基上时往往无法生长。改进培养方法和提高认识对于识别该病原体从而实现靶向抗生素治疗很重要。

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