普瑞巴林（辉瑞公司）。
Pregabalin (Pfizer).
作者信息
Huckle Richard
机构信息
Axovan Ltd., Innovation Center, Gewerbestrasse 16, CH-4123 Allschwil, Switzerland.
出版信息
Curr Opin Investig Drugs. 2004 Jan;5(1):82-9.
Pregabalin is a gamma-aminobutyric acid analog that is under development by Pfizer for the potential treatment of central nervous system disorders, including epilepsy, neuropathic pain, fibromyalgia and generalized anxiety disorder. By April 2003, Pfizer had filed for approval of pregabalin in Europe for neuropathic pain and as an adjunctive therapy for epilepsy, and in October 2003 an NDA was filed for these indications and generalized anxiety disorder. At this time, phase III trials in fibromyalgia were ongoing.
普瑞巴林是一种γ-氨基丁酸类似物，辉瑞公司正在对其进行研发，用于潜在治疗中枢神经系统疾病，包括癫痫、神经性疼痛、纤维肌痛和广泛性焦虑症。截至2003年4月，辉瑞公司已在欧洲申请批准普瑞巴林用于治疗神经性疼痛以及作为癫痫的辅助治疗药物，并且在2003年10月提交了针对这些适应症以及广泛性焦虑症的新药申请。此时，针对纤维肌痛的III期试验正在进行中。
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