对青蛙嗅球的推测性γ-氨基丁酸能反馈输入：一项采用逆行轴突追踪和γ-氨基丁酸免疫组织化学的双重标记研究。

Presumptive GABAergic feedback input to the frog olfactory bulb: a double labelling study with retrograde axonal tracing and GABA immunohistochemistry.

作者信息

Kratskin I, Kenigfest N, Repérant J, Rio J P, Vesselkin N

机构信息

Laboratory of Evolution of Neuronal Interaction, Sechenov Institute of Evolutionary Physiology and Biochemistry, St. Petersburg, Russia.

出版信息

Brain Res. 1992 May 22;581(1):171-4. doi: 10.1016/0006-8993(92)90360-l.

DOI:10.1016/0006-8993(92)90360-l

PMID:1498669

Abstract

The localization of gamma-aminobutyric acid (GABA)-immunoreactive neurons that project to the main olfactory bulb in the frog was studied by combining GABA immunohistochemistry with retrograde axonal tracing. Double-labelled neurons were observed in the dorsal, medial and lateral pallial areas involved in reciprocal connections with the main olfactory bulb. GABA-immunoreactive cell bodies constituted only a part of the population of bulbopetal neurons in each pallial region. This suggests that bulbopetal neurons in the frog pallium belong to neuronal populations which differ in their neurotransmitter specificities. The bulbopetal GABA-immunoreactive pallial neurons may be the source of GABAergic feedback input to the frog main olfactory bulb.

摘要

通过将γ-氨基丁酸（GABA）免疫组织化学与逆行轴突追踪相结合，研究了青蛙中投射到主嗅球的GABA免疫反应性神经元的定位。在与主嗅球有相互连接的背侧、内侧和外侧脑皮层区域观察到了双标记神经元。GABA免疫反应性细胞体仅构成每个脑皮层区域向嗅球投射神经元群体的一部分。这表明青蛙脑皮层中的向嗅球投射神经元属于神经递质特异性不同的神经元群体。向嗅球投射的GABA免疫反应性脑皮层神经元可能是青蛙主嗅球GABA能反馈输入的来源。