Huibers Marcus J H, Beurskens Anna J H M, Van Schayck Constant P, Bazelmans Ellen, Metsemakers Job F M, Knottnerus J Andre, Bleijenberg Gijs
Department of Epidemiology, Maastricht University, The Netherlands.
Br J Psychiatry. 2004 Mar;184:240-6. doi: 10.1192/bjp.184.3.240.
Fatigue is a common complaint that may lead to long-term sick leave and work disability.
To assess the efficacy of cognitive-behavioural therapy by general practitioners for unexplained, persistent fatigue among employees.
A randomised controlled trial, using a pre-randomisation design in primary care, investigated 151 employees on sick leave with fatigue. Participants in the experimental group were offered five to seven 30 min sessions of cognitive-behavioural therapy by a general practitioner; those in the control group were offered no treatment. Main outcome measures (fatigue severity, self-reported absenteeism, registered absenteeism and clinical recovery) were assessed at 4 months, 8 months and 12 months.
At baseline, 44% of the patients already met research criteria for chronic fatigue syndrome. There was no significant difference between the experimental group and the control group on primary or secondary outcomes at any point.
Cognitive-behavioural therapy by general practitioners for unexplained, persistent fatigue did not prove to be an effective intervention. Since these doctors were unable to deliver this therapy effectively under ideal circumstances, it is unlikely that doctors in routine practice would be more successful in doing so.
疲劳是一种常见的主诉,可能导致长期病假和工作能力丧失。
评估全科医生进行认知行为疗法对员工不明原因的持续性疲劳的疗效。
一项随机对照试验,采用初级保健中的预随机设计,对151名因疲劳而休病假的员工进行了调查。实验组的参与者由一名全科医生提供五到七次30分钟的认知行为疗法治疗;对照组不接受治疗。在4个月、8个月和12个月时评估主要结局指标(疲劳严重程度、自我报告的缺勤率、登记的缺勤率和临床康复情况)。
在基线时,44%的患者已符合慢性疲劳综合征的研究标准。在任何时间点,实验组和对照组在主要或次要结局上均无显著差异。
全科医生进行的认知行为疗法对不明原因的持续性疲劳并未被证明是一种有效的干预措施。由于这些医生在理想情况下都无法有效地实施这种疗法,因此常规执业医生更不可能成功做到这一点。