Jason G W, Pajurkova E M
Division of Psychology, Foothills Hospital.
Cortex. 1992 Jun;28(2):241-60. doi: 10.1016/s0010-9452(13)80052-4.
A right-handed man suffered aneurysmal haemorrhage with lesions of the genu and body of the corpus callosum and the inferomedial frontal lobes bilaterally (right more than left). He exhibited remarkable breakdown in behavioural unity characterized by conflict between the two sides of the body, actions inconsistent with verbalizations, and internal conflict over control of the left hand. A major feature of the deficit was its temporal variability. This is interpreted as reflecting intermittent failure of metacontrol processes, which are neural mechanisms for maintaining behavioural unity. Medial frontal structures and their interconnections through the corpus callosum appear particularly important in the maintenance of metacontrol.
一名惯用右手的男性发生动脉瘤性出血，胼胝体膝部和体部以及双侧额叶内下侧（右侧比左侧更严重）出现损伤。他表现出明显的行为统一性破坏，其特征为身体两侧之间的冲突、行为与言语不一致以及左手控制方面的内心冲突。这种缺陷的一个主要特征是其时间变异性。这被解释为反映了元控制过程的间歇性失败，元控制过程是维持行为统一性的神经机制。内侧额叶结构及其通过胼胝体的相互连接在维持元控制方面显得尤为重要。
