Goldenberg G, Wimmer A, Holzner F, Wessely P
Cortex. 1985 Mar;21(1):135-48. doi: 10.1016/s0010-9452(85)80021-6.
A 40 year old right-handed woman suffered hemorrhage from an anterior cerebral artery aneurysm. CT scan showed destruction of the anterior two thirds of the corpus callosum, both cingulate gyri, and the white matter underlying the medial frontal lobes. The left limbs displayed apraxia on verbal command, in imitation, and in actual object use. There were antagonistic actions of both hands, and the patient accused her left hand of disobeying her. We interpret the leftsided apraxia as resulting from a lack of interhemispheric transfer combined with a deficit in ipsilateral motor control stemming from damage to the left supplementary motor area. Right frontal lobe damage may have impaired the motor learning capacity of the right hemisphere and thus its ability to compensate for the lack of left hemisphere motor control.
一名40岁的右利手女性因大脑前动脉动脉瘤出血。CT扫描显示胼胝体前三分之二、双侧扣带回以及额叶内侧下方的白质受损。左侧肢体在言语指令、模仿及实际使用物体时表现出失用症。双手出现拮抗动作，患者指责其左手不听使唤。我们将左侧失用症解释为是由于半球间传递缺失，以及左侧辅助运动区受损导致同侧运动控制缺陷所致。右侧额叶损伤可能损害了右半球的运动学习能力，进而影响其补偿左半球运动控制缺失的能力。
