Shih Marianne T, Singh Ajay K, Wang Ay-Ming, Patel Sneha
Department of Diagnostic Radiology, William Beaumont Hospital, Royal Oak, MI 48073, USA.
Curr Probl Diagn Radiol. 2004 Mar-Apr;33(2):85-95. doi: 10.1016/j.cpradiol.2003.11.002.
Magnetic resonance (MR) spectroscopy is a noninvasive imaging tool that provides information on various metabolite concentrations within brain lesions. The biochemical information obtained with MR spectroscopy, along with the morphologic appearance of a lesion on MR imaging, allows for better characterization and improved diagnostic ability. Lactic acid is an end product of anaerobic metabolism. Under conditions of anaerobic metabolism or inflammation, lactate levels become elevated and a characteristic peak at 1.3 ppm is detected on MR spectroscopy. This review will discuss the significance of lactate as a metabolite and will describe various brain lesions and disease conditions in which elevated lactate levels are detected.
磁共振（MR）波谱是一种非侵入性成像工具，可提供有关脑病变内各种代谢物浓度的信息。通过MR波谱获得的生化信息，以及病变在MR成像上的形态学表现，有助于更好地进行特征描述并提高诊断能力。乳酸是无氧代谢的终产物。在无氧代谢或炎症条件下，乳酸水平会升高，并且在MR波谱上会检测到1.3 ppm处的特征峰。本综述将讨论乳酸作为一种代谢物的意义，并描述检测到乳酸水平升高的各种脑病变和疾病情况。
