光电子共振捕获电离（PERCI）：一种用于有机化合物软电离的新技术。

Photoelectron resonance capture ionization (PERCI): a novel technique for the soft-ionization of organic compounds.

作者信息

LaFranchi Brian W, Petrucci Giuseppe A

机构信息

Department of Chemistry, University of Vermont, Burlington, Vermont 05405, USA.

出版信息

J Am Soc Mass Spectrom. 2004 Mar;15(3):424-30. doi: 10.1016/j.jasms.2003.11.015.

DOI:10.1016/j.jasms.2003.11.015

PMID:14998546

Abstract

Photoelectron resonance capture ionization (PERCI) is demonstrated as a sensitive ionization technique involving minimal fragmentation of organic molecules. PERCI has been used successfully to softly and efficiently ionize both strongly UV absorbing and non-absorbing molecules. Tunable low energy (<1 eV) electrons are generated by focusing a pulsed UV laser on an aluminum photocathode in the presence of gas phase analyte. Negative ions are formed through a resonance electron capture process. Mass analysis is done using a reflectron time-of-flight mass spectrometer. PERCI is demonstrated for a number of gas phase compounds and simple mixtures, including sulfur hexafluoride, nitrobenzene, nitrophenol, 2-pentanone, hexanal, heptanal, and octanal. In all cases the molecular ion (or M - H) was observed to be the dominant peak. The 1sigma limit of detection was estimated to be on the order of 10(6) molecules in the ionization region.

摘要

光电子共振捕获电离（PERCI）被证明是一种灵敏的电离技术，它使有机分子的碎片化程度降至最低。PERCI已成功用于对强吸收紫外线和不吸收紫外线的分子进行温和且高效的电离。在气相分析物存在的情况下，通过将脉冲紫外激光聚焦在铝光电阴极上产生可调谐的低能量（<1 eV）电子。负离子通过共振电子捕获过程形成。使用反射式飞行时间质谱仪进行质量分析。已对多种气相化合物和简单混合物进行了PERCI分析，包括六氟化硫、硝基苯、硝基苯酚、2-戊酮、己醛、庚醛和辛醛。在所有情况下，均观察到分子离子（或M - H）是主峰。估计电离区域的1σ检测限约为10⁶个分子。