一只被困的北海狮（北海狗属）身上发生的伴有肺转移的多形性横纹肌肉瘤。

Pleomorphic rhabdomyosarcoma with pulmonary metastasis in a stranded Steller (northern) sea lion (Eumetopias jubatus).

作者信息

Zabka T S, Buckles E L, Gulland F M D, Haulena M, Naydan D K, Lowenstine L J

机构信息

Pathology Service, Veterinary Medical Teaching Hospital, University of California, Davis, CA 95616, USA.

出版信息

J Comp Pathol. 2004 Feb-Apr;130(2-3):195-8. doi: 10.1016/j.jcpa.2003.08.001.

DOI:10.1016/j.jcpa.2003.08.001

PMID:15003477

Abstract

A Steller (northern) sea lion (SSL), stranded in northern California in July 2000 had an anaplastic pleomorphic rhabdomyosarcoma in the latissimus dorsi muscle, with pulmonary metastasis. Diagnosis was based on light and electron microscopy and immunohistochemistry. Death was attributed to multiple parasitic and bacterial lesions. The SSL is of special concern because, for unknown reasons, the global population has declined by 50% over the last decade. Published post-mortem data, however, are scarce. This case report highlights several disease conditions that affect this species and is the first report of a malignant neoplasm in a free-ranging SSL.

摘要

2000年7月，一头斯特勒海狮（北海狮）搁浅在加利福尼亚州北部，其背阔肌患有间变性多形性横纹肌肉瘤，并伴有肺转移。诊断基于光镜、电镜检查及免疫组化。死亡原因是多种寄生虫和细菌感染。北海狮是特别受关注的物种，因为不明原因，其全球数量在过去十年间减少了50%。然而，已发表的尸检数据很少。本病例报告强调了影响该物种的几种疾病情况，并且是自由放养的北海狮发生恶性肿瘤的首例报告。