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高分辨率超声对肘部尺神经病变的诊断价值

Diagnostic value of high-resolution sonography in ulnar neuropathy at the elbow.

作者信息

Beekman R, Schoemaker M C, Van Der Plas J P L, Van Den Berg L H, Franssen H, Wokke J H J, Uitdehaag B M J, Visser L H

机构信息

Department of Neurology, St. Elisabeth Hospital, TweeSteden Hospital, Tilburg, VU Medical Centre, Amsterdam, the Netherlands.

出版信息

Neurology. 2004 Mar 9;62(5):767-73. doi: 10.1212/01.wnl.0000113733.62689.0d.

Abstract

OBJECTIVE

To determine the diagnostic value of high-resolution sonography in ulnar neuropathy at the elbow (UNE).

METHODS

Sonographic ulnar nerve diameter measurement was compared at three levels around the medial epicondyle with a criterion standard including clinical and electrophysiologic characteristics in a cohort of 123 patients presenting with clinical signs of UNE. UNE or probable UNE was diagnosed in 84 patients and a different condition in 39 patient controls. Reference values were obtained in 56 healthy volunteers.

RESULTS

One hundred thirty-six affected arms were studied in 123 patients (UNE in 82, probable UNE in 9, and a different condition in 45 affected arms). Patients with UNE had a larger ulnar nerve diameter than patient controls (p < 0.0001). The sensitivity of sonography was 80%, specificity 91%, positive likelihood ratio 9, and negative likelihood ratio 0.2. The highest diagnostic yield was found in patients in whom electrodiagnostic studies showed signs of ulnar neuropathy but could not localize the lesion (17/20 cases, 86%) and in patients who had motor conduction velocity slowing across the elbow without conduction block (32/37 cases, 86%).

CONCLUSIONS

High-resolution sonography is an accurate and easily applied test for the diagnosis of UNE. The authors recommend its use in addition to electrodiagnostic studies because it improves the reliability of the diagnosis of UNE.

摘要

目的

确定高分辨率超声检查对肘部尺神经病变(UNE)的诊断价值。

方法

对123例有UNE临床症状的患者,在肱骨内上髁周围三个水平测量超声下尺神经直径,并与包括临床和电生理特征的标准对照进行比较。84例患者被诊断为UNE或可能的UNE,39例患者为对照。在56名健康志愿者中获取参考值。

结果

对123例患者的136条患侧手臂进行研究(82条手臂为UNE,9条为可能的UNE,45条患侧手臂为其他情况)。UNE患者的尺神经直径大于对照患者(p < 0.0001)。超声检查的敏感性为80%,特异性为91%,阳性似然比为9,阴性似然比为0.2。在电诊断研究显示尺神经病变迹象但无法定位病变的患者中(17/20例,86%)以及在肘部运动传导速度减慢但无传导阻滞的患者中(32/37例,86%)发现诊断率最高。

结论

高分辨率超声检查是诊断UNE的一种准确且易于应用的检查方法。作者建议除电诊断研究外使用该方法,因为它可提高UNE诊断的可靠性。

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