Chen Gang, Hou Shi-xiang, Hu Ping, He Ning, Zhu Ya-ning, Cao Lun
Pharmaceutical Laboratory of Chinese Materia Medica, West China School of Pharmacy, Sichuan University, Chengdu 610041, Sichuan, China.
Zhongguo Zhong Yao Za Zhi. 2003 Mar;28(3):223-6.
To investigate the stability of chlorogenic acid in extract of flos lonicerae in different conditions.
The stability of chlorogenic acid in extract of flos lonicerae in phosptat buffe with different pH values, methanol, ethanol and different base solutions(Ca(OH)2 and NaOH) was investigated by the classical isothermal method.
The experiments showed the chlorogenic acid in extract of flos lonicerae was more stable in acidic water than in basic water. It was stable in these organic solutions and base solution[Ca(OH)2].
In different conditions, the stability of chlorogenic acid in extract of flos lonicerae was different. It provided a reference to the extraction and analysis of chlorogenic acid and production of chlorogenic acid preparation.
考察不同条件下金银花提取物中绿原酸的稳定性。
采用经典恒温法考察金银花提取物中绿原酸在不同pH值的磷酸盐缓冲液、甲醇、乙醇及不同碱溶液（Ca(OH)₂和NaOH）中的稳定性。
实验表明，金银花提取物中的绿原酸在酸性水中比在碱性水中更稳定。它在这些有机溶液和碱溶液[Ca(OH)₂]中稳定。
在不同条件下，金银花提取物中绿原酸的稳定性不同。这为绿原酸的提取、分析及绿原酸制剂的生产提供了参考。
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