Wang Jie, Jing Lu
Xiyuan Hospital of China Academy of TCM, Beijing 100091, China.
Zhongguo Zhong Yao Za Zhi. 2003 Sep;28(9):795-8.
It is the key problem of TCM study in the new times to strengthen the research and application of Chinese herbs and its compound prescription directed by TCM theory by combining medicine and drugs, accelerating the creation and construction of modern the new system. In the study of compound, animal mode should be set up by the combination of modern experimental method according to TCM clinical requirements. A breakthrough in compound prescription needs to be found out from observation of pharmacodynamics and analysis of clinical therapy. Methodology and clarification of effective materials should be paid enough attention to in study the pharmacokinetics of the compounds. Since the therapeutic effects of compound prescriptions are different, or even opposite to itself under different Syndromes, it is so important to pay attention to Syndrome Differention. Multiple ways of TCM study have given active exploration on the developing of TCM academic level from different aspects. The aim of constructing a system of developing TCM and Syndrome-corresponding compound prescription is to build up a normalized standard of new and highly effective theory in treating disease clinically, designing methodology, Syndrome-corresponding prescription and monitor the compound prescription used. In this way, a new TCM clinical standard could be set up in Chinese medicine and its compound prescription in clinical experiments to raise the medical level continuously.
结合医学与药学，加强以中医理论为指导的中药及其复方的研究与应用，加速构建现代新体系，是新时期中医研究的关键问题。在复方研究中，应根据中医临床需求，结合现代实验方法建立动物模型。复方的突破需要从药效学观察和临床治疗分析中寻找。在研究复方药代动力学时，应充分重视方法学和有效物质的阐明。由于复方在不同证候下的治疗效果不同，甚至相反，因此重视辨证尤为重要。中医多种研究方法从不同方面对提升中医学术水平进行了积极探索。构建中医及方证相应复方研发体系的目的，是建立临床治疗疾病、设计方法学、方证相应处方及监测复方应用的规范化高效新理论标准。通过这种方式，在中医及其复方的临床试验中建立新的中医临床标准，以不断提高医疗水平。
