Vilella Anna, Bayas Jose-Maria, Diaz Maria-Teresa, Guinovart Caterina, Diez Consolación, Simó Dulcis, Muñoz Amparo, Cerezo Javier
Adults Vaccination Centre, Preventive Medicine Department, UASP IDIBAPS, Clínic Hospital, Barcelona, Spain.
Prev Med. 2004 Apr;38(4):503-9. doi: 10.1016/j.ypmed.2003.12.005.
Noncompliance with vaccination schedules undermines the potential benefits of immunization. The purpose of this study was to evaluate whether a reminder of the next vaccine dose sent by the Short Messaging Service (SMS) to the vaccinee's mobile phone increases compliance with hepatitis A + B and hepatitis A vaccination schedule.
In this experimental, controlled study, the study group comprised travelers who went to the Internacional-Clínic Vaccination Centre between the 1st June and 30th September of 2001 for the standard immunization schedule against hepatitis A + B and against hepatitis A. Trained health-care workers entered the data into a computer to generate text messages reminding vaccinees of their scheduled doses. Two control groups, one from the same period of the same year including travelers from the third office (Control 2001) and the second, all travelers seen in the same period of the previous year (Control 2000), were used.
For the second hepatitis A + B dose, compliance in the study group (Message Groups) was 88.4% (83.3-92.2); in the Control 2001, 80.7% (76.3-84.4, relative risk [RR] 1.10 [1.02-1.17]); and in the Control 2000, 77.2% (73.3-80.5, RR 1.15 [1.07-1.22]). For the third hepatitis A + B vaccine dose, results were 47.1% (40.5-53.8); 26.9% (22.8-31.7, RR 1.75 [1.41-2.17]); and 23.6% (20.1-27.4, RR 2.00 [1.63-2.45]), respectively. As for the hepatitis A vaccine, compliance rates for the second dose were 27.7% (23.9-31.9); 16.4% (14.4-18.6, RR 1.69 [1.40-2.04]); and 13.2% (11.6-14.9, RR 2.10 [1.75-2.54]); respectively.
SMS seems to be an effective tool for increasing compliance with vaccination schedules.
不遵守疫苗接种计划会削弱免疫接种的潜在益处。本研究的目的是评估通过短信服务（SMS）向疫苗接种者手机发送下次疫苗接种提醒是否能提高甲型肝炎+乙型肝炎和甲型肝炎疫苗接种计划的依从性。
在这项实验性对照研究中，研究组包括2001年6月1日至9月30日期间前往国际临床疫苗接种中心进行甲型肝炎+乙型肝炎和甲型肝炎标准免疫接种计划的旅行者。训练有素的医护人员将数据输入计算机以生成短信提醒疫苗接种者其预定剂量。使用了两个对照组，一个来自同一年同期，包括来自第三个办公室的旅行者（2001年对照组），另一个是上一年同期就诊的所有旅行者（2000年对照组）。
对于第二剂甲型肝炎+乙型肝炎疫苗，研究组（短信组）的依从率为88.4%（83.3 - 92.2）；2001年对照组为80.7%（76.3 - 84.4，相对风险[RR]1.10[1.02 - 1.17]）；2000年对照组为77.2%（73.3 - 80.5，RR 1.15[1.07 - 1.22]）。对于第三剂甲型肝炎+乙型肝炎疫苗，结果分别为47.1%（40.5 - 53.8）；26.9%（22.8 - 31.7，RR 1.75[1.41 - 2.17]）；和23.6%（20.1 - 27.4，RR 2.00[1.63 - 2.45]）。至于甲型肝炎疫苗，第二剂的依从率分别为27.7%（23.9 - 31.9）；16.4%（14.4 - 18.6，RR 1.69[1.40 - 2.04]）；和13.2%（11.6 - 14.9，RR 2.10[1.75 - 2.54]）。
短信似乎是提高疫苗接种计划依从性的有效工具。
