Mistiaen Patriek, Poot Else, Hickox Sophie, Jochems Christ, Wagner Cordula
Netherlands Institute of Health Services Research, Utrecht, The Netherlands.
Dermatol Nurs. 2004 Feb;16(1):43-6, 49-57.
Intertrigo is an inflammatory dermatosis of the skin folds of the body, for which a large variety of topical medications may be recommended. A systematic literature review was performed to find scientific evidence for preventing and treating intertrigo within the nursing domain. Seven electronic databases were searched with a simple broad-scope search strategy. The aim was to identify all publications that concerned intertrigo itself and other conditions that were related to intertriginous regions. This search produced 451 references. A final set of 24 studies was retained and analyzed on content and methodologic quality. Most studies concerned treatments with antifungals or disinfectants in heterogeneous research samples, with only small subsamples of people with intertrigo. Six studies were randomized controlled trials. In general, the methodologic quality of the studies was poor. The analyzed studies provided no scientific evidence for any type of nursing prevention or treatment strategy. There is a great need for well-designed clinical studies on intertrigo.
擦烂红斑是一种发生于身体皮肤褶皱处的炎症性皮肤病，针对此病可能会推荐多种局部用药。我们进行了一项系统的文献综述，以寻找护理领域内预防和治疗擦烂红斑的科学证据。采用简单的广泛搜索策略对七个电子数据库进行了检索。目的是识别所有与擦烂红斑本身以及与擦烂性区域相关的其他病症有关的出版物。此次检索产生了451篇参考文献。最终保留了24项研究，并对其内容和方法学质量进行了分析。大多数研究涉及在异质性研究样本中使用抗真菌药或消毒剂进行治疗，仅有一小部分擦烂红斑患者的子样本。六项研究为随机对照试验。总体而言，这些研究的方法学质量较差。分析的研究未提供任何类型护理预防或治疗策略的科学证据。非常需要针对擦烂红斑开展设计良好的临床研究。
