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心源性休克的治疗策略

Therapeutic Strategies for Cardiogenic Shock.

作者信息

Yazbek Naji F., Kleiman Neal S.

机构信息

Section of Cardiology, Baylor College of Medicine, Methodist Debakey Heart Center, 6565 Fannin Boulevard, F1090, Houston, TX 77030, USA.

出版信息

Curr Treat Options Cardiovasc Med. 2004 Feb;6(1):29-41. doi: 10.1007/s11936-004-0012-9.

DOI:10.1007/s11936-004-0012-9
PMID:15023282
Abstract

Cardiogenic shock is a devastating consequence of acute myocardial infarction; it is associated with an extremely high mortality. Treatment strategies should be focused on prompt reperfusion, as well as hemodynamic support. The optimal approach for therapy is emergent angiography and revascularization using percutaneous coronary intervention or coronary artery bypass surgery, with the assistance of intra-aortic balloon pump counterpulsation. Several adjunctive pharmacologic agents, particularly inotropic drugs and vasopressors, are also helpful for hemodynamic support. However, these agents have not been shown to provide a survival benefit, and their use is primarily based on clinical experience.

摘要

心源性休克是急性心肌梗死的灾难性后果,其死亡率极高。治疗策略应侧重于及时再灌注以及血流动力学支持。最佳治疗方法是在主动脉内球囊反搏的辅助下,通过经皮冠状动脉介入治疗或冠状动脉旁路移植术进行紧急血管造影和血运重建。几种辅助药物,特别是强心药物和血管升压药,对血流动力学支持也有帮助。然而,这些药物尚未显示出能带来生存获益,其使用主要基于临床经验。

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The role of the renin-angiotensin system in the development of cardiovascular disease.肾素-血管紧张素系统在心血管疾病发展中的作用。
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