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下颌骨牵张成骨术治疗小颌畸形和严重上气道阻塞

Mandibular distraction for micrognathia and severe upper airway obstruction.

作者信息

Mandell David L, Yellon Robert F, Bradley James P, Izadi Keyoumars, Gordon Christopher B

机构信息

Department of Pediatric Otolaryngology, Children's Hospital of Pittsburgh, PA 15213, USA.

出版信息

Arch Otolaryngol Head Neck Surg. 2004 Mar;130(3):344-8. doi: 10.1001/archotol.130.3.344.

DOI:10.1001/archotol.130.3.344
PMID:15023845
Abstract

OBJECTIVE

To determine whether the use of mandibular distraction osteogenesis (DOG) can help to avoid tracheotomy or achieve decannulation in patients with mandibular hypoplasia and severe upper airway obstruction.

DESIGN

Retrospective medical record review (spanning a 27-month period).

SETTING

Tertiary care children's hospital.

SUBJECTS

Group A (n=8) was composed of infants with Pierre Robin sequence and no tracheotomy (mean age, 2.5 months); group B (n=6), older nontracheotomized micrognathic children with obstructive sleep apnea (OSA) (mean age, 69 months); and group C (n=12), tracheotomized children with complex congenital syndromes (mean age, 33 months).

INTERVENTION

Bilateral mandibular DOG with endoscopic (n=24) and/or radiographic (n=17) airway evaluation (mean follow-up, 16 months [range, 2-42 months]).

OUTCOME MEASURES

Group A, tracheotomy avoidance; group B, resolution of OSA (clinically or on polysomnography); and group C, decannulation.

RESULTS

Group A, 7 patients (88%) successfully avoided tracheotomy; group B, 5 patients (83%) had resolution of OSA; and group C, 2 patients (17%) underwent decannulation.

CONCLUSIONS

Mandibular DOG (1) allows tracheotomy avoidance in infants with isolated Pierre Robin sequence and (2) relieves OSA in older micrognathic children without tracheotomy. However, mandibular DOG does not frequently lead to decannulation in tracheotomized patients with complex congenital syndromes.

摘要

目的

确定下颌骨牵张成骨术(DOG)的应用是否有助于避免下颌骨发育不全和严重上呼吸道梗阻患者进行气管切开术或实现拔管。

设计

回顾性病历审查(为期27个月)。

地点

三级医疗儿童医院。

研究对象

A组(n = 8)由患有皮埃尔·罗宾序列征且未行气管切开术的婴儿组成(平均年龄2.5个月);B组(n = 6)为年龄较大的未行气管切开术的小颌畸形且患有阻塞性睡眠呼吸暂停(OSA)的儿童(平均年龄69个月);C组(n = 12)为行气管切开术的患有复杂先天性综合征的儿童(平均年龄33个月)。

干预措施

采用双侧下颌骨DOG并进行内镜(n = 24)和/或影像学(n = 17)气道评估(平均随访16个月[范围2 - 42个月])。

观察指标

A组为避免气管切开术;B组为OSA缓解(临床或多导睡眠图检查);C组为拔管。

结果

A组,7例患者(88%)成功避免了气管切开术;B组,5例患者(83%)的OSA得到缓解;C组,2例患者(17%)进行了拔管。

结论

下颌骨DOG(1)可使孤立性皮埃尔·罗宾序列征婴儿避免气管切开术,(2)可缓解未行气管切开术的年龄较大的小颌畸形儿童的OSA。然而,下颌骨DOG在患有复杂先天性综合征的气管切开术患者中并不常导致拔管。

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