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双侧口腔内牵张成骨术治疗儿童早期严重先天性下颌骨发育不全

Bilateral intra-oral distraction osteogenesis for the management of severe congenital mandibular hypoplasia in early childhood.

作者信息

Sadakah Abdelfattah A, Elshall Mohammad A, Farhat Amgad A

机构信息

Department of Oral & Maxillofacial Surgery, Faculty of Dentistry, Tanta University, Egypt.

出版信息

J Craniomaxillofac Surg. 2009 Jun;37(4):216-24. doi: 10.1016/j.jcms.2008.10.014. Epub 2008 Dec 9.

Abstract

INTRODUCTION

Young children with severe mandibular hypoplasia usually present with varying degrees of peripheral airway obstruction and difficulty with feeding. Early treatment is important for such children. Distraction osteogenesis (DO) using intra-oral devices provides an excellent alternative when other surgical techniques do not prove to be satisfactory.

AIM OF THE WORK

To evaluate the long-term efficacy of intra-oral bilateral DO in the treatment of severe congenital mandibular hypoplasia in early childhood.

PATIENTS AND METHODS

Seven patients (4 females and 3 males), their ages ranged from 7 months to 8 years (with a mean of 34 months). They presented with severe congenital mandibular hypoplasia with obstructive sleep apnoea and difficulty in feeding. All patients were treated with bilateral mandibular DO, using an intra-oral unidirectional unburied distractor. The average follow-up period was 3.7 years (range, 2-5 years).

RESULTS

The patients were successfully treated using bilateral intra-oral unidirectional distractor by the use of a modified technique. After completion of distraction, retrognathia was corrected in all patients. The "subjective" symptoms had disappeared completely or had been alleviated. The mean effective airway space increase (defined by the lateral cephalograms measurements) was 70.5% (range, 31-105%, p<0.01) when compared with pre-distraction. The apnoea/hypopnoea index was lowered from 60 (9.8-126.5) to 1.57 (0-16.4) and the sleep apnoea symptoms had disappeared. The mean oxygen saturation increase was from 80% to 98% post-distraction.

CONCLUSION

DO can consistently produce a measurable cross-section airway improvement in patients as young as 7 months.

摘要

引言

患有严重下颌发育不全的幼儿通常会出现不同程度的外周气道阻塞和喂养困难。早期治疗对这类儿童很重要。当其他手术技术效果不佳时,使用口腔内装置进行牵张成骨术(DO)是一种很好的选择。

研究目的

评估口腔内双侧牵张成骨术治疗幼儿严重先天性下颌发育不全的长期疗效。

患者与方法

7例患者(4例女性,3例男性),年龄7个月至8岁(平均34个月)。他们患有严重先天性下颌发育不全,伴有阻塞性睡眠呼吸暂停和喂养困难。所有患者均采用口腔内单向非埋入式牵张器进行双侧下颌牵张成骨术。平均随访期为3.7年(范围2 - 5年)。

结果

采用改良技术,使用双侧口腔内单向牵张器成功治疗了这些患者。牵张完成后,所有患者的下颌后缩均得到矫正。“主观”症状完全消失或有所缓解。与牵张前相比,平均有效气道空间增加(通过头颅侧位片测量)为70.5%(范围31 - 105%,p<0.01)。呼吸暂停/低通气指数从60(9.8 - 126.5)降至1.57(0 - 16.4),睡眠呼吸暂停症状消失。牵张后平均血氧饱和度从80%升至98%。

结论

牵张成骨术能持续改善7个月大患者的气道横截面积。

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