Nayak Kapadi Surendra, Narayanan Shankar, Naik Ramadas, Khadilkar Urmila Niranjan
Department of Pathology, Kasturba Medical College, Mangalore.
Indian J Pathol Microbiol. 2003 Jul;46(3):459-61.
Prolymphocytic leukaemia is a rare subtype of chronic lymphocytic leukaemia. Three such cases were reported here along with clinical details. All these cases were seen in males above 5th decade. These patients showed moderate to massive splenomegaly, inconspicuous lymphadenoapthy in two cases and one with minimal lymphadenopathy. Peripheral smear showed high leukocyte count with more than 55% of prolymphocytes. Bone marrow aspiration showed diffuse involvement and in one with minimal lymphadenopathy, lymphnode aspiration showed prolymphocytes. All the three patients died within a year after diagnosis.
幼淋巴细胞白血病是慢性淋巴细胞白血病的一种罕见亚型。本文报告了3例此类病例及临床细节。所有这些病例均见于50岁以上男性。这些患者表现为中度至重度脾肿大，2例患者淋巴结肿大不明显，1例患者淋巴结肿大轻微。外周血涂片显示白细胞计数高，幼淋巴细胞占比超过55%。骨髓穿刺显示弥漫性受累，1例淋巴结肿大轻微的患者，淋巴结穿刺显示有幼淋巴细胞。所有3例患者在诊断后1年内死亡。
