Malik Reeni, Bharadwaj V K
Department of Pathology, Gandhi Medical College, Bhopal, MP.
Indian J Pathol Microbiol. 2003 Oct;46(4):559-62.
The aim of this case series is to evaluate the pattern of breast lumps in males and females with special reference to spectrum of lesions in females below 40 years of age. A 20 years retrospective study was undertaken from the records of the department of Pathology, Bhopal. The lesions were classified into benign and malignant. In young females histological pattern was analyzed in various age groups. A total of 1824 cases were studied. 1724 (94.5%) cases were seen in females and 100 (5.5%) in males. There were 1276 (74%) females below 40 years of age and 448 (26%) were above 40 years of age. In young females 1136 (89%) lesions were benign and 140 (11%) were malignant lumps. Fibrocystic disease in 60 (49%) cases constituted the largest group of benign lumps followed by 30 (24.5%) cases of inflammatory lesion in older females. The mean age of malignant tumors was 34.1 in young females and 51.4 in females above 40. Infiltrating duct carcinoma constituted 83.5% of malignant tumors in young females and 86.1% in older females.
本病例系列的目的是评估男性和女性乳腺肿块的模式，特别关注40岁以下女性的病变谱。对博帕尔病理科的记录进行了一项为期20年的回顾性研究。病变分为良性和恶性。对年轻女性不同年龄组的组织学模式进行了分析。共研究了1824例病例。1724例（94.5%）见于女性，100例（5.5%）见于男性。40岁以下女性有1276例（74%），40岁以上女性有448例（26%）。在年轻女性中，1136例（89%）病变为良性，140例（11%）为恶性肿块。60例（49%）纤维囊性疾病构成了最大的良性肿块组，其次是30例（24.5%）老年女性的炎症性病变。年轻女性恶性肿瘤的平均年龄为34.1岁，40岁以上女性为51.4岁。浸润性导管癌在年轻女性恶性肿瘤中占83.5%，在老年女性中占86.1%。
