Levy Angela D, Hobbs Christine M
Department of Radiologic Pathology, Armed Forces Institute of Pathology, 6825 16th St NW, Washington, DC 20306-6000, USA.
Radiographics. 2004 Mar-Apr;24(2):565-87. doi: 10.1148/rg.242035187.
Meckel diverticulum is the most common congenital anomaly of the gastrointestinal tract, occurring in 2%-3% of the population. It results from improper closure and absorption of the omphalomesenteric duct. Meckel diverticulum is the most common end result of the spectrum of omphalomesenteric duct anomalies, which also include umbilicoileal fistula, umbilical sinus, umbilical cyst, and a fibrous cord connecting the ileum to the umbilicus. The formation of Meckel diverticulum occurs with equal frequency in both sexes, but symptoms from complications are more common in male patients. Sixty percent of patients come to medical attention before 10 years of age, with the remainder of cases manifesting in adolescence and adulthood. Heterotopic gastric and pancreatic mucosa are frequently found histologically within the diverticula of symptomatic patients. The most common complications are hemorrhage from peptic ulceration, small intestinal obstruction, and diverticulitis. Although the clinical, pathologic, and radiologic features of the complications of Meckel diverticulum are well known, the diagnosis of Meckel diverticulum is difficult to establish preoperatively.
梅克尔憩室是胃肠道最常见的先天性异常,在人群中的发生率为2% - 3%。它是由于卵黄管闭合和吸收不当所致。梅克尔憩室是卵黄管异常谱系中最常见的最终结果,卵黄管异常还包括脐回肠瘘、脐窦、脐囊肿以及连接回肠与脐的纤维索。梅克尔憩室的形成在男女中发生率相等,但并发症引起的症状在男性患者中更为常见。60%的患者在10岁前就医,其余病例在青春期和成年期出现症状。在有症状患者的憩室内,组织学检查常发现异位胃黏膜和胰腺黏膜。最常见的并发症是消化性溃疡出血、小肠梗阻和憩室炎。尽管梅克尔憩室并发症的临床、病理和放射学特征已为人熟知,但术前很难确诊梅克尔憩室。