Rembouskos G, Cicero S, Longo D, Vandecruys H, Nicolaides K H
Harris Birthright Research Centre for Fetal Medicine, King's College Hospital Medical School, London, UK.
Ultrasound Obstet Gynecol. 2004 Mar;23(3):232-6. doi: 10.1002/uog.952.
To evaluate the benefit of three-dimensional (3D) ultrasound in the examination of the fetal nasal bone at 11-14 weeks of gestation.
We examined the fetal nasal bone in 120 stored volumes acquired transabdominally with a 3D scanner from singleton pregnancies at 11-14 weeks of gestation. The volume acquisition had been performed following conventional ultrasound examination that had demonstrated presence of the fetal nasal bone. The volumes were obtained with two-dimensional (2D) start images in transverse, coronal mid-sagittal, parasagittal and oblique longitudinal sections of the fetal head.
In the transverse and coronal sections, a satisfactory image demonstrating presence of the nasal bone was achieved in only three and one, respectively, of the 20 volumes that we obtained. In mid-sagittal sections, the nasal bone was always visible when the angle was within a range of 30-60 degrees, without the need for sectional image analysis. None of the images with an angle >60 degrees or <30 degrees was satisfactory. In the parasagittal sections with the fetal profile at 45 degrees, a good-quality image of the nasal bone was possible in all cases that were examined, irrespective of the distance from the mid-sagittal plane. In the oblique longitudinal sections with the fetal profile at 45 degrees, there were 10 volumes where the 2D start section was at 0-25 degrees from the midline and in all these cases the nasal bone was successfully visualized. In contrast, only 5/20 cases where the 2D start section was at 25-90 degrees from the midline provided a satisfactory image demonstrating the nasal bone. In 5/10 volumes obtained with the fetus facing downwards the nasal bone was visible in both the 2D and 3D images.
In a 3D volume the extent to which the nasal bone can be demonstrated to be present in a given reconstructed section is entirely dependent on obtaining a good initial 2D view.
评估三维（3D）超声在妊娠11 - 14周时检查胎儿鼻骨的益处。
我们使用3D扫描仪经腹检查了120例妊娠11 - 14周单胎妊娠的储存容积中的胎儿鼻骨。容积采集是在常规超声检查显示胎儿鼻骨存在后进行的。容积是通过胎儿头部的横切面、冠状面中矢状面、旁矢状面和斜矢状面的二维（2D）起始图像获得的。
在横切面和冠状面中，我们获得的20个容积中分别只有3个和1个获得了显示鼻骨存在的满意图像。在中矢状面中，当角度在30 - 60度范围内时，鼻骨总是可见的，无需进行断层图像分析。角度>60度或<30度的图像均不满意。在胎儿轮廓为45度的旁矢状面中，所有检查的病例无论距中矢状面的距离如何都能获得鼻骨的高质量图像。在胎儿轮廓为45度的斜矢状面中，有10个容积的2D起始切面与中线成0 - 25度角，在所有这些病例中鼻骨都成功显示。相比之下，2D起始切面与中线成25 - 90度角的20个病例中只有5个提供了显示鼻骨的满意图像。在胎儿面部朝下获得的10个容积中有5个在2D和3D图像中都可见鼻骨。
在3D容积中，在给定重建切面中显示鼻骨存在的程度完全取决于获得良好的初始2D视图。
