Itoh Hiroshi, Wada Toshiro, Michikata Kaori, Sato Yuichiro, Seguchi Tomoko, Akiyama Yutaka, Kataoka Hiroaki
Second Department of Pathology, Miyazaki Medical College, Kiyotake, Japan.
Pathol Int. 2004 Apr;54(4):279-83. doi: 10.1111/j.1440-1827.2004.01621.x.
A solid well-circumscribed ovarian tumor in a 63-year-old Japanese woman is reported. Histologically, the tumor consisted predominantly of a hemangiomatous component with a small cyst lined by a respiratory ciliated epithelium. The remaining ovarian stroma showed a marked proliferation of luteinized cells that were strongly positive for inhibin immunohistochemically. Neither dermoid nor other teratomatous components were found, even in the serial sections of the tumor. To date, vascular tumors of the ovary are uncommon and some cases of ovarian hemangioma have been reported. However, their origin, whether a monodermal teratoma or a true neoplasm arising in the ovarian stroma, has not yet been elucidated. When a hemangiomatous proliferation is found in an ovarian tumor, a thorough microscopic search for teratomatous components is necessary before diagnosing the tumor as a pure hemangioma.
报告了一名63岁日本女性的一例边界清晰的实性卵巢肿瘤。组织学上,肿瘤主要由血管瘤成分构成,有一个由呼吸道纤毛上皮衬覆的小囊肿。其余卵巢间质显示黄素化细胞显著增生,免疫组化检测抑制素呈强阳性。即使在肿瘤的连续切片中,也未发现皮样囊肿或其他畸胎瘤成分。迄今为止,卵巢血管肿瘤并不常见,已有一些卵巢血管瘤病例的报道。然而,其起源,无论是单胚层畸胎瘤还是起源于卵巢间质的真正肿瘤,尚未阐明。当在卵巢肿瘤中发现血管瘤样增生时,在将肿瘤诊断为纯血管瘤之前,有必要进行全面的显微镜检查以寻找畸胎瘤成分。