Zamore Phillip D
Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, Massachusetts 01605, USA.
Curr Biol. 2004 Mar 9;14(5):R198-200. doi: 10.1016/j.cub.2004.02.021.
The three-dimensional structure of an siRNA bound to the tombusvirus p19 protein--a suppressor of gene silencing--provides a first glimpse into how plant viruses can defeat their host's anti-viral RNAi defenses.
与番茄丛矮病毒p19蛋白（一种基因沉默抑制子）结合的小干扰RNA（siRNA）的三维结构，首次揭示了植物病毒如何抵御宿主的抗病毒RNA干扰防御机制。
