Perret J-L, Lagauche D, Favier J-C, Rey P, Bigois L, Adam F
Fédération de médecine, HIA Legoust, Metz-Armee.
Presse Med. 2004 Feb 14;33(3):170-1. doi: 10.1016/s0755-4982(04)98515-6.
Scurvy can occur in hospitalized patients despite vitamin supplementation.
A 63 Year-old patient who had spent several weeks in intensive care developed an unexplained anemia and ecchymoses. Despite daily administration of 130 mg/day of vitamin C since his admission, his ascorbic acid blood levels had collapsed. Administration of 1g/day relieved the symptoms within four weeks.
Whether a deficiency had existed prior to admission or not, scurvy developed during the week of intensive care despite parenteral nutrition supplying a daily dose of 130 mg of vitamin C. Such deficiencies decompensated in surgical situations remain a reality in developed countries.
In certain pathological contexts and in all the growing number of cases in elderly patients and many surgical indications, the need for vitamin C supplementation has to be defined. The needs at that particular time must be taken into account and the prior nutritional status.
尽管补充了维生素，坏血病仍可能在住院患者中发生。
一名63岁的患者在重症监护室度过了几周后出现了不明原因的贫血和瘀斑。自入院以来，尽管每天给予130毫克/天的维生素C，但其血液中的抗坏血酸水平仍大幅下降。每天给予1克维生素C在四周内缓解了症状。
无论入院前是否存在缺乏情况，尽管肠外营养每天提供130毫克维生素C，但坏血病仍在重症监护期间出现。在发达国家，这种在手术情况下出现的缺乏情况仍然存在。
在某些病理情况下，以及在老年患者和许多手术指征中越来越多的病例中，必须确定补充维生素C的必要性。必须考虑到特定时期的需求以及先前的营养状况。
