Adult Intensive Care, Department of Anesthesiology, Pharmacology and Intensive Care, University Hospital of Geneva (HUG), Geneva, Switzerland.
Eur J Clin Nutr. 2013 Aug;67(8):881-2. doi: 10.1038/ejcn.2013.42. Epub 2013 Apr 3.
Scurvy, a severe form of vitamin C deficiency, killed scores of people until its cause and treatment were firmly established at the end of the eighteenth century. Since then, cases have surged periodically around the world, mostly in developing countries and during times of war and famine. In developed countries, scurvy is still endemic and evidence is growing that vitamin C deficiency might affect up to 30 percent of the population. Low socio-economic status, alcoholism, severe psychiatric illness leading to poor nutrition and critical illness are significant risk factors. We hereby report the case of a patient admitted in a Swiss intensive care unit of a tertiary teaching hospital and presenting with clinical signs and symptoms of severe vitamin C deficiency.
坏血病是一种严重的维生素 C 缺乏症,在 18 世纪末其病因和治疗方法得到明确之前,曾导致大量患者死亡。此后,该病在全球范围内周期性地爆发,主要发生在发展中国家以及战争和饥荒时期。在发达国家,坏血病仍然流行,越来越多的证据表明,维生素 C 缺乏可能影响高达 30%的人群。社会经济地位低、酗酒、严重的精神疾病导致营养不良以及重病是重要的危险因素。在此,我们报告了一位患者的病例,该患者在瑞士一所三级教学医院的重症监护病房住院,出现了严重维生素 C 缺乏的临床症状和体征。