Ol'shanskiĭ V O, Novozhilova E N, Dvornichenko V V, Mitrokhin S D
Moskovskiĭ nauchno-issledovatel'skiĭ institut im. P. A. Gertsena, gorodskaia onkologicheskaia bol'nitsa #62, Moskva; Irkutskiĭ oblastnoĭ onkodispanser.
Vestn Otorinolaringol. 2004(1):61-3.
The study was made of the condition of voice prostheses Provox and Blom-Singer in 27 patients wearing them. The prostheses were to be replaced by new ones as they lost impermeability for water. The prostheses were used for 6 months to 2 years. At the prosthesis removal from the tracheoesophageal bypass it was found that the esophageal flange and protective valve were contaminated with fungi and pathogenic bacteria. The valve was deformed, had limited motility and did not close tightly the esophageal opening of the prosthesis as the result of which liquid leaked into the airways. Bacteriological examination identified C.albicans, C.krusei, C.glabralis in 11 patients. Nistatin, flucostat, fluconasol, amphotericin were used in antifungal therapy. Prophylactic use of these drugs against fungi prolonged use of the prostheses 2-fold.
对27名佩戴Provox和Blom-Singer语音假体的患者的假体状况进行了研究。当假体失去防水性时，需更换新的假体。假体使用时间为6个月至2年。在从气管食管旁路取出假体时发现，食管凸缘和保护瓣膜被真菌和病原菌污染。瓣膜变形，活动受限，不能紧密关闭假体的食管开口，导致液体漏入气道。细菌学检查在11名患者中鉴定出白色念珠菌、克柔念珠菌、光滑念珠菌。抗真菌治疗使用了制霉菌素、氟康唑、氟康唑、两性霉素。预防性使用这些抗真菌药物使假体的使用时间延长了一倍。
