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[孢子丝菌样非典型分枝杆菌感染。抗生素单一疗法]

[Sporotrichoid atypical mycobacterial infections. Antibiotic monotherapy].

作者信息

Bormann G, Marsch W C

机构信息

Universitätsklinik und Poliklinik für Dermatologie und Venerologie der Martin-Luther-Universität Halle-Wittenberg, Halle (Saale).

出版信息

Hautarzt. 2004 Mar;55(3):292-5. doi: 10.1007/s00105-003-0679-y.

Abstract

Sporotrichoid forms of atypical mycobacterial infections usually do not show a tendency to spontaneous healing. The therapy of choice in such cases is systemic antibiotics. We report three cases of sporotrichoid atypical mycobacterial infections of the skin which healed completely under long-term monotherapy with modern antibiotics (levofloxacin, clarithromycin, minocycline). We recommend confirming the diagnosis by means of culture, followed by monotherapy with low side-effect antibiotics, based on sensitivity studies. If pathogen proof is obtained by PCR, antibiotic therapy should be based on the known sensitivity of the pathogen in question.

摘要

非典型分枝杆菌感染的孢子丝菌病样型通常没有自愈倾向。此类病例的首选治疗方法是全身使用抗生素。我们报告了3例皮肤孢子丝菌病样非典型分枝杆菌感染病例,这些病例在使用现代抗生素(左氧氟沙星、克拉霉素、米诺环素)进行长期单一治疗后完全治愈。我们建议通过培养来确诊,然后根据药敏试验,使用低副作用抗生素进行单一治疗。如果通过聚合酶链反应获得病原体证据,抗生素治疗应基于所涉病原体已知的敏感性。

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