Straub M, Hautmann R E
Abteilung Urologie und Kinderurologie, Arbeitsgruppe Harnsteine, Universitätsklinikum Ulm.
Urologe A. 2004 Apr;43(4):440-9. doi: 10.1007/s00120-003-0514-1.
During the last 2 decades in Germany, only minor efforts were expended for the prevention of urinary stones. Substantial technical progress simplified the treatment of existing calculi; thus, it was more convenient to treat a new stone than to prevent its recurrence. But times change! In these days of financial squeeze in the medical system, prevention becomes more attractive. Nevertheless, strategies for kidney stone prevention developed. Established concepts for dietary advice were rejected due to the results of new randomized studies. Moreover, new pharmacological substances were introduced for metaphyalxis. The new concepts are feasible for the daily routine. For some treatment modalities in stone prevention, there is valid evidence from the literature, which should encourage us to adopt these modalities in the future. A number of drugs are used as "good common practice" without any proof from a randomized trial. Often prospective and valid studies are not available. The present paper intends to describe the status quo of nephrolithiasis prevention in Germany, focussing on confirmed data and unsolved problems.
在过去20年里,德国在预防尿石症方面投入的精力很少。巨大的技术进步简化了现有结石的治疗;因此,治疗新结石比预防其复发更方便。但时代在变!在当今医疗系统面临资金紧张的时期,预防变得更具吸引力。尽管如此,肾结石预防策略仍在不断发展。由于新的随机研究结果,已确立的饮食建议概念被摒弃。此外,还引入了用于预防的新药。这些新概念适用于日常临床实践。对于结石预防的一些治疗方式,文献中有有效的证据,这应鼓励我们在未来采用这些方式。许多药物被用作“良好的常规做法”,但没有随机试验的任何证据。通常也没有前瞻性的有效研究。本文旨在描述德国肾结石预防的现状,重点关注已证实的数据和未解决的问题。