Biboulet Philippe, Morau Didier, Aubas Pierre, Bringuier-Branchereau Sophie, Capdevila Xavier
Department of Anesthesiology and Critical Care, Centre Hospitalo-Universitaire de Montpellier, Montpellier, France.
Reg Anesth Pain Med. 2004 Mar-Apr;29(2):102-9. doi: 10.1016/j.rapm.2003.11.006.
The authors compared the analgesic effects and quality of rehabilitation of three analgesic techniques after total-hip arthroplasty in a double-blind, randomized trial.
Forty-five patients were assigned to 1 of 3 groups, patient-controlled analgesia with morphine (PCA), femoral nerve block (FNB), or psoas compartment block (PCB). At the end of the procedure performed under general anesthesia, nerve blocks using 2 mg/kg of 0.375% bupivacaine and 2 microg/kg of clonidine were performed in the FNB (n = 16) and PCB (n = 15) groups. In the recovery room, all 3 groups received initial intravenous morphine titration if their pain score was higher than 30 on a 100-mm visual analog scale (VAS), and then a PCA device was initiated. Morphine consumption was the primary end point to assess postoperative analgesia.
After extubation (H0), morphine titration was higher in the PCA group (P <.05). During the first 4 postoperative hours (H0 to H4), morphine consumption per hour and VAS pain score were lower in the PCB group (P <.05). After H4, there was no difference in morphine consumption and VAS among groups, either at rest or during mobilization. After H4, morphine consumption remained lower than 0.5 mg/h, and VAS remained lower than 30 mm in the 3 groups. In 4 patients of the PCB group, an epidural diffusion was noted. Hip mobility and length of stay in the rehabilitation center were not different among the groups.
PCA is an efficient and safe analgesia technique. FNB and PCB should not be used routinely after total-hip arthroplasty.
作者在一项双盲随机试验中比较了全髋关节置换术后三种镇痛技术的镇痛效果和康复质量。
45例患者被分配到3组中的1组,即吗啡患者自控镇痛(PCA)组、股神经阻滞(FNB)组或腰大肌间隙阻滞(PCB)组。在全身麻醉下完成手术结束时,FNB组(n = 16)和PCB组(n = 15)使用2 mg/kg的0.375%布比卡因和2 μg/kg的可乐定进行神经阻滞。在恢复室,如果所有3组患者在100 mm视觉模拟量表(VAS)上的疼痛评分高于30分,则接受初始静脉吗啡滴定,然后启动PCA装置。吗啡消耗量是评估术后镇痛的主要终点。
拔管后(H0),PCA组的吗啡滴定量更高(P <.05)。术后前4小时(H0至H4),PCB组每小时的吗啡消耗量和VAS疼痛评分更低(P <.05)。H4之后,各组在休息或活动时的吗啡消耗量和VAS评分均无差异。H4之后,3组的吗啡消耗量均低于0.5 mg/h,VAS评分均低于30 mm。PCB组有4例患者出现硬膜外扩散。各组之间的髋关节活动度和在康复中心的住院时间无差异。
PCA是一种有效且安全的镇痛技术。全髋关节置换术后不应常规使用FNB和PCB。