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皮节体感诱发电位在腰骶部椎管狭窄症中的临床应用

The clinical use of dermatomal somatosensory evoked potentials in lumbosacral spinal stenosis.

作者信息

Storm Seneca A, Kraft George H

机构信息

Department of Rehabilitation Medicine, University of Washington, 1959 NE Pacific Street, Seattle, WA 98195-6490, USA.

出版信息

Phys Med Rehabil Clin N Am. 2004 Feb;15(1):107-15. doi: 10.1016/s1047-9651(03)00107-4.

Abstract

DSEPs provide clinicians with a safe, noninvasive technique useful in determining which patients with anatomic spinal stenosis have the added component of neurogenic compromise. Based on physiologic principles, level-by-level prolongation of DSEP latencies, reduction of amplitude, asymmetry, or a complete absence of response is associated with dysfunction in that particular afferent neurologic pathway. This dysfunction does not correspond to the exact level of stenosis noted on MRI because the rootlets in the lumbar and sacral regions pass through multiple spinal segments as they course rostrally through the spinal canal. Given that LSSS typically develops over time, the degree of abnormality likely would correspond to the physiologic slowing occurring in the multiple rootlets of the cauda equina. These recordings are not easy to perform and interpret, but when done correctly, they provide the best evidence for the type of neurophysiologic dysfunction in LSSS that responds favorably to surgical decompression. Similarly, DSEPs might provide a means of neurophysiologically monitoring clinically significant findings in a program of conservative management.

摘要

皮层体感诱发电位(DSEP)为临床医生提供了一种安全、无创的技术,有助于确定哪些患有解剖性椎管狭窄的患者存在神经源性损伤这一附加因素。根据生理学原理,DSEP潜伏期逐节延长、波幅降低、不对称或完全无反应与该特定传入神经通路的功能障碍有关。这种功能障碍并不对应于MRI上所显示的狭窄的确切节段,因为腰骶部的神经根在向头侧穿过椎管时会经过多个脊柱节段。鉴于腰椎管狭窄症(LSSS)通常是随时间发展的,异常程度可能与马尾神经多个神经根中发生的生理性减慢相对应。这些记录不容易进行和解读,但如果操作正确,它们能为LSSS中对手术减压有良好反应的神经生理功能障碍类型提供最佳证据。同样,DSEP可能为保守治疗方案中神经生理学监测临床显著发现提供一种方法。

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