Bakunzi F R
Department of Animal Health, University of North West, PO Box 1372, Mafikeng 2745, South Africa.
J S Afr Vet Assoc. 2003 Sep;74(3):82-3. doi: 10.4102/jsava.v74i3.516.
A survey was conducted on the occurrence of anthelmintic resistance of nematodes in communally grazed goats in a semi-arid area in South Africa. In herds belonging to 10 small-holder goat farmers, the efficacies of fenbendazole, levamisole and rafoxanide were tested by faecal egg count reduction (FECR) tests. Efficacies of 80% were considered a threshold for anthelmintic resistance. The FECR tests showed that all drugs tested more than 80% effective in most instances, but there were notable exceptions. In 1 case, rafoxanide was only 31% effective and in another case fenbendazole was only 47% effective. The occurrence of anthelmintic resistance in this farming sector is of concern. Steps should be taken to prevent its further spread and to avoid the development of a situation as on numerous commercial sheep farms in South Africa where resistance is very common.
在南非一个半干旱地区，对 communal 放牧山羊体内线虫的驱虫抗性发生情况进行了一项调查。在属于 10 个小农户山羊养殖户的畜群中，通过粪便虫卵计数减少（FECR）试验测试了芬苯达唑、左旋咪唑和雷复尼特的疗效。80%的疗效被视为驱虫抗性的阈值。FECR 试验表明，在大多数情况下，所有测试药物的有效性均超过 80%，但也有显著例外。在 1 个案例中，雷复尼特的有效性仅为 31%，在另一个案例中，芬苯达唑的有效性仅为 47%。该养殖部门出现驱虫抗性令人担忧。应采取措施防止其进一步传播，并避免出现南非众多商业绵羊养殖场那样抗性非常普遍的情况。 （注：communal 这个词不太明确准确意思，可能影响整体译文准确性，此处按原样翻译）
