Darenius K
Department of Obstetrics and Gynaecology, Swedish University of Agricultural Sciences, Uppsala.
Acta Vet Scand. 1992;33(2):147-60. doi: 10.1186/BF03547321.
Fifteen mares which had each lost their pregnancies 2 to 8 times during the preceding 6 years were used in a study comprising 1 or 2 breeding seasons for each mare. During the research period all 15 mares conceived and 10 of the mares had normal pregnancies in the 1st experimental year. Five mares resorbed/aborted once or twice during the 1st year. This was followed by a pregnancy that terminated in a live foal. Histopathological examinations of uterine biopsies showed a wide range of histopathological conditions, from absence of changes excessive for the mare's age and parity to the most severe changes of the endometrium. Most likely, endometritis, acute as well as chronic degenerative endometritis, is the most common cause of early foetal death in the mare. Good breeding management is essential and was often enough to make the mares produce a foal. Additional treatment was needed in some of the mares and was based on the course of the conceptus loss and the condition of the endometrium, as determined by clinical, histological, bacteriological and cytological examinations.
15匹母马参与了一项研究,这些母马在过去6年中每匹都有过2至8次妊娠失败经历,每匹母马的研究周期为1或2个繁殖季节。在研究期间,所有15匹母马均受孕,其中10匹母马在第一个实验年度内妊娠正常。5匹母马在第一年出现过1至2次吸收/流产情况。随后的一次妊娠产下了活驹。对子宫活检组织进行的组织病理学检查显示,组织病理学状况差异很大,从不存在与母马年龄和胎次不相称的变化到子宫内膜最严重的变化。最有可能的是,子宫内膜炎,包括急性和慢性变性子宫内膜炎,是母马早期胎儿死亡最常见的原因。良好的繁殖管理至关重要,而且往往足以使母马产下驹。部分母马需要额外治疗,治疗依据是通过临床、组织学、细菌学和细胞学检查确定的胚胎丢失过程和子宫内膜状况。