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年龄相关性黄斑变性治疗的当前概念与最新进展

Current concepts and recent advances in the management of age-related macular degeneration.

作者信息

Byrne S, Beatty S

机构信息

Department of Ophthalmology, Royal Victoria Infirmary, Newcastle-upon-Tyne, UK.

出版信息

Ir J Med Sci. 2003 Oct-Dec;172(4):185-90. doi: 10.1007/BF02915287.

DOI:10.1007/BF02915287
PMID:15029987
Abstract

BACKGROUND

Age-related macular degeneration (AMD) is the leading cause of visual impairment and blindness in the Western World in those aged 65 and older. At present, several treatment modalities are utilised and several more are undergoing investigation in an attempt to retard the occurrence and progression of this devastating condition.

AIMS

To provide the non-ophthalmologist with an understanding of the current treatment options available to patients suffering from all variants of AMD.

METHODS

Medline and Embase search.

RESULTS

Several treatment modalities have been investigated and utilised in the treatment of all variants of this condition. While promising results have been reported, no treatment is ideal.

CONCLUSION

While no curative treatment for this condition currently exists, early recognition and treatment, if indicated, have been shown to reduce the risk of severe vision loss in patients with this condition.

摘要

背景

年龄相关性黄斑变性(AMD)是西方世界65岁及以上人群视力损害和失明的主要原因。目前,人们采用了多种治疗方式,还有几种正在进行研究,试图延缓这种破坏性疾病的发生和发展。

目的

让非眼科医生了解目前可用于患有各种类型AMD患者的治疗选择。

方法

检索Medline和Embase数据库。

结果

已经对几种治疗方式进行了研究并用于治疗这种疾病的各种类型。虽然报告了一些有前景的结果,但没有一种治疗方法是理想的。

结论

虽然目前尚无治愈这种疾病的方法,但早期识别并在有指征时进行治疗已被证明可降低患有这种疾病的患者严重视力丧失的风险。

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1
Current concepts and recent advances in the management of age-related macular degeneration.年龄相关性黄斑变性治疗的当前概念与最新进展
Ir J Med Sci. 2003 Oct-Dec;172(4):185-90. doi: 10.1007/BF02915287.
2
Treatment of age-related macular degeneration.年龄相关性黄斑变性的治疗
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Nippon Ganka Gakkai Zasshi. 2007 Mar;111(3):232-68; discussion 269.
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Recent advances in the management of age-related macular degeneration.年龄相关性黄斑变性治疗的最新进展
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本文引用的文献

1
Dietary antioxidant intake and incidence of early age-related maculopathy: the Blue Mountains Eye Study.膳食抗氧化剂摄入量与早发性年龄相关性黄斑病变的发病率:蓝山眼研究
Ophthalmology. 2002 Dec;109(12):2272-8. doi: 10.1016/s0161-6420(02)01263-0.
2
Retinal pigment epithelium translocation after choroidal neovascular membrane removal in age-related macular degeneration.年龄相关性黄斑变性中脉络膜新生血管膜切除术后视网膜色素上皮移位
Ophthalmology. 2002 Aug;109(8):1492-8. doi: 10.1016/s0161-6420(02)01099-0.
3
Improvement in quality of life from photodynamic therapy: a Canadian perspective.
Can J Ophthalmol. 2001 Oct;36(6):332-8. doi: 10.1016/s0008-4182(01)80120-4.
4
The cost-effectiveness of photodynamic therapy for fellow eyes with subfoveal choroidal neovascularization secondary to age-related macular degeneration.光动力疗法对年龄相关性黄斑变性继发的黄斑中心凹下脉络膜新生血管对侧眼的成本效益分析。
Ophthalmology. 2001 Nov;108(11):2051-9. doi: 10.1016/s0161-6420(01)00764-3.
5
A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E, beta carotene, and zinc for age-related macular degeneration and vision loss: AREDS report no. 8.一项关于高剂量补充维生素C、维生素E、β-胡萝卜素和锌对年龄相关性黄斑变性及视力丧失影响的随机、安慰剂对照临床试验:年龄相关性眼病研究组报告第8号。
Arch Ophthalmol. 2001 Oct;119(10):1417-36. doi: 10.1001/archopht.119.10.1417.
6
Photodynamic therapy of subfoveal choroidal neovascularization in age-related macular degeneration with verteporfin: two-year results of 2 randomized clinical trials-tap report 2.维替泊芬光动力疗法治疗年龄相关性黄斑变性中心凹下脉络膜新生血管:两项随机临床试验的两年结果——TAP报告2
Arch Ophthalmol. 2001 Feb;119(2):198-207.
7
External beam irradiation of subfoveal choroidal neovascularization complicating age-related macular degeneration: one-year results of a prospective, double-masked, randomized clinical trial.年龄相关性黄斑变性并发中心凹下脉络膜新生血管的外照射治疗:一项前瞻性、双盲、随机临床试验的一年结果
Arch Ophthalmol. 2001 Feb;119(2):171-80.
8
Transpupillary thermotherapy (TTT) for the treatment of choroidal neovascularisation.经瞳孔温热疗法(TTT)治疗脉络膜新生血管。
Br J Ophthalmol. 2001 Feb;85(2):173-8. doi: 10.1136/bjo.85.2.173.
9
The role of oxidative stress in the pathogenesis of age-related macular degeneration.氧化应激在年龄相关性黄斑变性发病机制中的作用。
Surv Ophthalmol. 2000 Sep-Oct;45(2):115-34. doi: 10.1016/s0039-6257(00)00140-5.
10
Submacular surgery trials randomized pilot trial of laser photocoagulation versus surgery for recurrent choroidal neovascularization secondary to age-related macular degeneration: I. Ophthalmic outcomes submacular surgery trials pilot study report number 1.黄斑下手术试验:年龄相关性黄斑变性继发复发性脉络膜新生血管激光光凝与手术对比的随机试点试验:I. 眼科结局 黄斑下手术试验试点研究报告编号1
Am J Ophthalmol. 2000 Oct;130(4):387-407. doi: 10.1016/s0002-9394(00)00729-7.