Woods E R, Helvie M A, Ikeda D M, Mandell S H, Chapel K L, Adler D D
Department of Radiology, Taubman Center, University of Michigan Hospitals, Ann Arbor 48109-0326.
AJR Am J Roentgenol. 1992 Sep;159(3):487-91. doi: 10.2214/ajr.159.3.1503011.
Our purpose was to determine the mammographic/galactographic features of solitary breast papillomas and to correlate these features with the pathologic findings.
Retrospective review of pathology files revealed 72 women in whom breast biopsy reports described a solitary papilloma. All patients with additional pathologic abnormalities were excluded from this study. Patients meeting the pathologic criteria and for whom mammograms, galactograms, or both were available and had been obtained within 6 months before biopsy were included. Twenty-four women met these criteria and form the basis of this study. Presenting clinical signs and symptoms were reviewed. Abnormal mammographic/galactographic findings were correlated with pathologic features.
Nipple discharge was present in 21 (88%) of 24 patients, two (8%) of 24 patients had abnormal findings on screening mammography, and one patient had a palpable mass that was visible on mammograms. Eight (42%) of 19 mammograms had abnormal findings, including dilated duct(s) in five cases (26%), nodules in two cases (11%), and microcalcifications in one case (5%). All technically adequate galactograms (13/15) had abnormal findings, with 12 (92%) of 13 showing an intraluminal filling defect. The other technically adequate galactogram (8%) showed only a solitary obstructed duct. Ductal dilatation was greatest at or central to the papilloma on 12 (92%) of 13 galactograms. Imaging features correlated well with the histologic findings.
Patients with solitary papillomas most commonly have nipple discharge, normal mammographic findings, and a galactographic filling defect. Galactography is useful for localizing papillomas.
我们的目的是确定孤立性乳腺导管内乳头状瘤的乳腺钼靶/乳腺导管造影特征,并将这些特征与病理结果相关联。
对病理档案进行回顾性分析,发现72例女性患者的乳腺活检报告中描述为孤立性乳头状瘤。所有伴有其他病理异常的患者均被排除在本研究之外。纳入符合病理标准且在活检前6个月内进行过乳腺钼靶、乳腺导管造影或两者检查且结果可用的患者。24名女性符合这些标准,构成了本研究的基础。回顾了患者的临床表现和症状。将乳腺钼靶/乳腺导管造影异常结果与病理特征相关联。
24例患者中有21例(88%)出现乳头溢液,24例患者中有2例(8%)在乳腺钼靶筛查中发现异常,1例患者有可触及肿块,在乳腺钼靶上可见。19例乳腺钼靶检查中有8例(42%)发现异常,包括5例(26%)导管扩张、2例(11%)结节和1例(5%)微钙化。所有技术上合格的乳腺导管造影(13/15)均有异常发现,13例中有12例(92%)显示管腔内充盈缺损。另一例技术上合格的乳腺导管造影(8%)仅显示一条孤立的阻塞性导管。13例乳腺导管造影中有12例(92%)在乳头状瘤处或其中心导管扩张最明显。影像学特征与组织学结果相关性良好。
孤立性乳头状瘤患者最常见的表现为乳头溢液、乳腺钼靶检查结果正常以及乳腺导管造影充盈缺损。乳腺导管造影有助于乳头状瘤的定位。