Sporton Simon C, Earley Mark J, Nathan Anthony W, Schilling Richard J
Department of Cardiology, Bart's and The London NHS Trust, London, United Kingdom.
J Cardiovasc Electrophysiol. 2004 Mar;15(3):310-5. doi: 10.1111/j.1540-8167.2004.03356.x.
The aim of this prospective randomized study was to compare the routine use of electroanatomic imaging (CARTO) with that of conventional fluoroscopically guided activation mapping (conventional) in an unselected population referred for catheter ablation. We sought to compare the two approaches with respect to procedure outcome and duration, radiation exposure, and cost.
All patients undergoing catheter ablation (with the exception of complete AV nodal ablation) were prospectively randomized to either a CARTO or conventional procedure for mapping and ablation. One hundred two patients were randomized. Acute procedural success was similar with either strategy (CARTO vs conventional 43/47 vs 51/55, P > 0.5), as was procedure duration (144 [58] vs 125 [48] min, P = 0.07 (mean [SD]). CARTO was associated with a substantial reduction in fluoroscopy time (9.3 [7.6] vs 28.8 [19.5] min, P < 0.001) and radiation dose (6.2 [6.1] vs 20.8 [32.7] Gray, P = 0.003). CARTO cases used fewer catheters (2.5 [0.7] vs 4.4 [1.1], P < 0.001), but catheter costs were higher (13.8 vs 9.3 units, P < 0.001, where one unit is equivalent to the cost of a nonsteerable quadripolar catheter).
For all catheter ablation procedures, even when a center's "learning curve" for CARTO is included, procedure duration and outcome are similar for CARTO and conventional procedures. CARTO is associated with drastically reduced fluoroscopy time and radiation dose. Although fewer catheters are used with CARTO, catheter costs remain higher.
这项前瞻性随机研究的目的是比较在未经过挑选的接受导管消融治疗的人群中,常规使用电解剖成像(CARTO)与传统荧光透视引导下激动标测(传统方法)的效果。我们试图在手术结果、持续时间、辐射暴露和成本方面比较这两种方法。
所有接受导管消融治疗的患者(除完全性房室结消融外)被前瞻性随机分为接受CARTO或传统方法进行标测和消融。102例患者被随机分组。两种策略的急性手术成功率相似(CARTO组与传统组分别为43/47 vs 51/55,P>0.5),手术持续时间也相似(144[58]分钟 vs 125[48]分钟,P = 0.07(均值[标准差]))。CARTO与透视时间大幅减少相关(9.3[7.6]分钟 vs 28.8[19.5]分钟,P<0.001)以及辐射剂量减少(6.2[6.1]格雷 vs 20.8[32.7]格雷,P = 0.003)。CARTO组使用的导管较少(2.5[0.7]根 vs 4.4[1.1]根,P<0.001),但导管成本较高(13.8单位 vs 9.3单位,P<0.001,其中一个单位相当于一根不可操控的四极导管的成本)。
对于所有导管消融手术,即使纳入了中心对CARTO的“学习曲线”,CARTO手术和传统手术的持续时间及结果相似。CARTO与显著减少的透视时间和辐射剂量相关。虽然CARTO使用的导管较少,但导管成本仍然较高。