Jericó Carlos, Knobel Hernando, Carmona Alexia, Sorli M Luisa, López-Colomés José Luis, Pedro-Botet Juan
Servicio de Medicina Interna-Enfermedades Infecciosas, Hospital del Mar, Universidad Autónoma de Barcelona, Spain.
Med Clin (Barc). 2004 Mar 6;122(8):298-300. doi: 10.1016/s0025-7753(04)74214-1.
Our goal was to assess the main characteristics of cardiovascular disease in HIV-infected patients on highly active antiretroviral therapy (HAART).
Retrospective analysis of the clinico-epidemiological characteristics of 16 HIV-infected patients treated with HAART who had suffered a cardiovascular event from a 1,459 patients' cohort.
Clinical presentation of cardiovascular disease was an acute coronary syndrome in 12 cases, ischemic stroke in 2 and peripheral vascular disease in 2. Patients included in the study had a mean of 3.2 cardiovascular risk factors, smoking and low HDL levels being the more prevalent risk factors. Eight (50%, 95% CI, 25-75%) patients fulfilled the criteria of metabolic syndrome. The mean CD4 count was 548 x 10(6)/l.
HIV-infected patients on HAART ha-ve a high cardiovascular risk. A strict management of modifiable risk factors must be warranted in these patients.
