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海绵体内颗粒细胞瘤

Intracavernous granular cell tumor.

作者信息

Inci Servet, Gülşen Salih, Söylemezoglu Figen, Kansu Tulay, Ozgen Tuncalp

机构信息

Department of Neurosurgery, School of Medicine, University of Hacettepe, Ankara, Turkey.

出版信息

Surg Neurol. 2004 Apr;61(4):384-90; discussion 390. doi: 10.1016/S0090-3019(03)00291-X.

Abstract

BACKGROUND

Granular cell tumors in the central nervous system are quite rare. To date, only 6 cases of granular cell tumor arising from cranial nerves have been reported in the literature. To the best of our knowledge, we present the first case of a predominant intracavernous granular-cell tumor arising from oculomotor nerve.

CASE PRESENTATION

A 42-year-old man presented with third-nerve paresis and decreased visual acuity on the left side. Magnetic resonance imaging showed a mainly intracavernous mass partially extending to the superior orbital fissure and entrance of the optic canal. Using a pterional craniotomy, the tumor was removed from within the cavernous sinus via combined superior and lateral intradural approach, and optic nerve was also decompressed. Histologically, the tumor was diagnosed as a granular cell tumor.

CONCLUSIONS

Although it is quite rare, granular cell tumor should be included into the differential diagnosis of intracavernous masses because surgical treatment is curative.

摘要

背景

中枢神经系统颗粒细胞瘤十分罕见。迄今为止,文献中仅报道过6例起源于颅神经的颗粒细胞瘤。据我们所知,我们报告了首例主要位于海绵窦内、起源于动眼神经的颗粒细胞瘤。

病例介绍

一名42岁男性,出现左侧动眼神经麻痹和视力下降。磁共振成像显示一个主要位于海绵窦内的肿块,部分延伸至眶上裂和视神经管入口。采用翼点开颅术,通过联合硬膜内上入路和侧入路从海绵窦内切除肿瘤,并对视神经进行减压。组织学检查诊断该肿瘤为颗粒细胞瘤。

结论

尽管颗粒细胞瘤非常罕见,但因其手术治疗可治愈,故应纳入海绵窦内肿块的鉴别诊断。

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