Fournier A M, Sosenko J M
University of Miami School of Medicine, Florida 33101.
Am J Med Sci. 1992 Aug;304(2):79-82. doi: 10.1097/00000441-199208000-00002.
A simple, inexpensive alternative to CD4 counts would facilitate the management of asymptomatic and early symptomatic patients with HIV infection. In this report, a high correlation was found between CD4 counts and total lymphocyte counts calculated from complete blood counts in a cohort of ambulatory HIV-infected patients. Using these data, patients with CD4 counts above and below 500 cells/mm3, 200 cells/mm3, and those with and without symptoms can be identified with a high degree of predictive value. The availability and lower cost of lymphocyte counts make them an attractive alternative to CD4 counts in managing asymptomatic and early symptomatic patients with HIV infection.
对于无症状和早期有症状的HIV感染患者，一种简单、廉价的替代CD4细胞计数的方法将有助于疾病管理。在本报告中，在一组门诊HIV感染患者中，发现CD4细胞计数与全血细胞计数计算得出的总淋巴细胞计数之间存在高度相关性。利用这些数据，可以高度准确地识别CD4细胞计数高于和低于500个细胞/立方毫米、200个细胞/立方毫米的患者，以及有症状和无症状的患者。淋巴细胞计数的可获取性和较低成本使其成为管理无症状和早期有症状HIV感染患者时替代CD4细胞计数的有吸引力的选择。
