Nestadt G, Romanoski A J, Samuels J F, Folstein M F, McHugh P R
Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD.
Am J Psychiatry. 1992 Sep;149(9):1228-33. doi: 10.1176/ajp.149.9.1228.
The aim of this study was to assess the relationships between specific personality disorders and DSM-III axis I conditions in a community sample.
A total of 810 subjects were examined by psychiatrists in the second stage of the Eastern Baltimore Mental Health Survey, part of the Epidemiological Catchment Area Program of the National Institute of Mental Health. A semistructured examination, the Standardized Psychiatric Examination, was employed to assess axis I and axis II conditions. Scales for compulsive and antisocial personality disorders were derived from DSM-III criteria. The relationships between scores on these personality disorder scales and the presence of generalized anxiety disorder, alcohol use disorders (alcohol abuse and alcohol dependence), and simple phobia were evaluated by using logistic regression.
Higher compulsive personality scores were associated with a greater odds of generalized anxiety disorder and simple phobia but a smaller odds of alcohol use disorders. In contrast, higher antisocial personality scores were associated with a greater odds of alcohol use disorders but a smaller odds of generalized anxiety disorder. There was no relationship between antisocial personality scores and simple phobia.
Personality disorders have specific relationships to axis I conditions, which suggests different vulnerabilities but also different protective influences.
本研究旨在评估社区样本中特定人格障碍与《精神疾病诊断与统计手册》第三版(DSM - III)轴I障碍之间的关系。
在东巴尔的摩心理健康调查的第二阶段,由精神科医生对总共810名受试者进行检查,该调查是美国国立精神卫生研究所流行病学集水区项目的一部分。采用一种半结构化检查,即标准化精神病学检查,来评估轴I和轴II障碍。强迫型和反社会型人格障碍量表源自DSM - III标准。通过逻辑回归评估这些人格障碍量表得分与广泛性焦虑症、酒精使用障碍(酒精滥用和酒精依赖)以及单纯恐惧症的存在之间的关系。
较高的强迫型人格得分与广泛性焦虑症和单纯恐惧症的较高发病几率相关,但与酒精使用障碍的发病几率较低相关。相比之下,较高的反社会型人格得分与酒精使用障碍的较高发病几率相关,但与广泛性焦虑症的发病几率较低相关。反社会型人格得分与单纯恐惧症之间没有关系。
人格障碍与轴I障碍存在特定关系,这表明存在不同的易感性,但也有不同的保护作用。