Kramer B A, Afrasiabi A, Pollock V E
Department of Psychiatry, University of Southern California School of Medicine, Los Angeles.
Am J Psychiatry. 1992 Sep;149(9):1258-60. doi: 10.1176/ajp.149.9.1258.
Twelve patients receiving ECT consented to random assignment to either intravenous or intramuscular administration of atropine for a total of 48 ECTs. There were no statistically significant differences between routes of administration in heart rate, blood pressures, or sialorrhea, but intravenous administration eliminated one injection per treatment and the development of dry mouth and tachycardia between the intramuscular injection and ECT. The authors recommend that atropine for ECT be administered intravenously.
12名接受电休克治疗（ECT）的患者同意随机分配接受静脉注射或肌肉注射阿托品，共进行48次ECT治疗。在心率、血压或流涎方面，给药途径之间没有统计学上的显著差异，但静脉注射每次治疗可减少一次注射，并消除了肌肉注射与ECT之间口干和心动过速的发生。作者建议ECT使用的阿托品采用静脉注射给药。
