Goldenberg M, Rabinovici J, Bider D, Lunenfeld B, Blankstein J, Weissenberg R
Department of Obstetrics and Gynecology, Chaim Sheba Medical Center, Tel Hashomer, Israel.
Andrologia. 1992 May-Jun;24(3):135-40. doi: 10.1111/j.1439-0272.1992.tb02626.x.
In this randomized prospective study, we determined the conception rate following intra-uterine insemination with washed and prepared sperm, or with the first portion of a split ejaculate, in couples with longstanding male (n = 27, 70 treatment cycles) or cervical infertility (n = 14, 29 treatment cycles). Folliculogenesis and ovulation were induced by human menopausal gonadotropin and human chorionic gonadotropin. Significantly more couples conceived in the male infertility group following intra-uterine insemination with washed sperm, than after intra-uterine insemination with split ejaculate (9 vs. 2; P less than 0.05), while no difference in pregnancy rate (2 vs. 2) was found by the two intra-uterine insemination methods in the cervical infertility group.
在这项随机前瞻性研究中，我们确定了对于患有长期男性不育（n = 27，70个治疗周期）或宫颈性不孕（n = 14，29个治疗周期）的夫妇，使用经洗涤和处理的精子进行宫内授精，或使用分段射精的第一部分进行宫内授精后的受孕率。通过人绝经期促性腺激素和人绒毛膜促性腺激素诱导卵泡生成和排卵。在男性不育组中，使用经洗涤精子进行宫内授精后的受孕夫妇明显多于使用分段射精进行宫内授精后的受孕夫妇（9例对2例；P小于0.05），而在宫颈性不孕组中，两种宫内授精方法的妊娠率没有差异（2例对2例）。
