Tan Hüseyin, Kiliçaslan Buket, Onbaş Omer, Büyükavci Mustafa
Department of Pediatric Neurology, Atatürk University Faculty of Medicine, Erzurum, Turkey.
Pediatr Neurol. 2004 Mar;30(3):207-9. doi: 10.1016/j.pediatrneurol.2003.08.007.
Acute disseminated encephalomyelitis is an immune-mediated demyelinating disorder usually encountered in children or adolescents and characterized by multifocal neurologic deficits of rapid onset. It is often preceded by various infectious diseases or vaccination, but acute disseminated encephalomyelitis developing after hepatitis A virus infection is rare. We present such a case in a 9-year-old patient who illustrates the importance of considering acute disseminated encephalomyelitis in patients who develop multifocal neurologic signs after hepatitis A virus infection. We suggest that patients with acute disseminated encephalomyelitis be screened for hepatitis A virus because of the occurrence of asymptomatic hepatitis A virus infection.
急性播散性脑脊髓炎是一种免疫介导的脱髓鞘疾病，常见于儿童或青少年，其特征为迅速出现的多灶性神经功能缺损。它常先于各种感染性疾病或疫苗接种出现，但甲型肝炎病毒感染后发生急性播散性脑脊髓炎较为罕见。我们报告了一名9岁患者的病例，该病例说明了在甲型肝炎病毒感染后出现多灶性神经体征的患者中考虑急性播散性脑脊髓炎的重要性。由于无症状甲型肝炎病毒感染的发生，我们建议对急性播散性脑脊髓炎患者进行甲型肝炎病毒筛查。
