Bouët V, Borel L, Harlay F, Gahéry Y, Lacour M
UMR 6149, Laboratoire de Neurobiologie Intégrative et Adaptative, 52 Faculté de St-Jérôme, CNRS/Université de Provence, Case 361, 13397 Marseille Cedex 20, France.
Behav Brain Res. 2004 Apr 2;150(1-2):207-16. doi: 10.1016/S0166-4328(03)00258-4.
The kinematics of treadmill locomotion in rats conceived, born, and raised in a hypergravity environment (HG: 2g) until the age of 3 months was investigated for 5 weeks after their exposition to earth's gravity. The locomotor performance of the HG rats (N=7) was compared to that of age-matched control rats (N=8) housed at 1g for the same period. Kinematic analysis of treadmill locomotion was performed up to 35 days of terrestrial life by an optoelectronic motion analyzer (ELITE system). Results showed that the HG rats exhibited a faster locomotor rhythm (increased number of steps/s), walked closer to the ground, and had a more dorsiflexed foot position. Also, HG rats had shorter steps. The data also highlight a fast adaptation to normal gravity since all the locomotor parameters returned to normal values within 3 weeks. The locomotor modifications may be seen as the persistence of a hypergravity-induced posturo-locomotor adaptation in the centrifuge and/or to more functional changes of sensorimotor systems. Because locomotor performance of HG rats is not severely affected, it is concluded that early development of locomotion processes is highly resistant to gravito-inertial changes.
研究了在超重力环境（HG：2g）中受孕、出生并饲养至3个月大的大鼠，在暴露于地球重力后5周内跑步机运动的运动学情况。将HG大鼠（N = 7）的运动表现与同期饲养在1g环境中的年龄匹配对照大鼠（N = 8）进行比较。通过光电运动分析仪（ELITE系统）对大鼠在地面生活35天内的跑步机运动进行运动学分析。结果表明，HG大鼠表现出更快的运动节奏（每秒步数增加），行走时离地面更近，且足部位置背屈更多。此外，HG大鼠的步幅较短。数据还突出显示了对正常重力的快速适应，因为所有运动参数在3周内恢复到正常水平。运动变化可能被视为在离心机中超重力诱导的姿势 - 运动适应的持续存在和/或感觉运动系统更功能性变化的结果。由于HG大鼠的运动表现未受到严重影响，得出的结论是，运动过程的早期发育对重力 - 惯性变化具有高度抗性。
