Muir A, Lever A, Moffett A
Research Group in Human Reproductive Immunobiology, Department of Pathology, University of Cambridge, Tennis Court Road, Cambridge CB2 1QP, UK.
Placenta. 2004 Apr;25 Suppl A:S16-25. doi: 10.1016/j.placenta.2004.01.012.
The placenta is unique amongst normal tissues in transcribing many different human endogenous retrovirus (HERV) families at high levels and this has led to the suggestion that HERVs may fulfil important functions in reproduction. This review discusses our current knowledge of the placental expression of HERVs, in particular the envelope proteins of ERV3 and HERV-W which may have critical roles in placental function.
胎盘在正常组织中独一无二，它能高水平转录许多不同的人类内源性逆转录病毒（HERV）家族，这使得有人提出HERV可能在生殖过程中发挥重要作用。本综述讨论了我们目前对HERV胎盘表达的了解，特别是ERV3和HERV-W的包膜蛋白，它们可能在胎盘功能中起关键作用。
