Stepanenko Irina, Kolchanov Nikolay
Institute of Cytology and Genetics, SB RAS, Lavrentieva 10, 630090, Novosibirsk, Russia.
Ann N Y Acad Sci. 2003 Dec;1010:16-8. doi: 10.1196/annals.1299.003.
The large volume of experimental data on apoptosis requires computer processing to systematize and provide an integrated "description of operation" of the gene network that regulates apoptosis in various cell types under varying effects. The database GeneNet contains the description of the apoptosis gene network: (http://wwwmgs.bionet.nsc.ru/systems/mgl/genenet), and the Transcription Regulatory Regions Database (TRRD) contains experimental data on transcription regulation of various genes, including apoptosis genes: (http://wwwmgs.bionet.nsc.ru/mgs/gnw/trrd/).
关于细胞凋亡的大量实验数据需要计算机处理,以便将调节不同细胞类型在不同影响下细胞凋亡的基因网络进行系统化,并提供其“操作描述”的整合。基因网络数据库(GeneNet)包含细胞凋亡基因网络的描述:(http://wwwmgs.bionet.nsc.ru/systems/mgl/genenet),转录调控区域数据库(TRRD)包含各种基因,包括细胞凋亡基因的转录调控实验数据:(http://wwwmgs.bionet.nsc.ru/mgs/gnw/trrd/)。