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[成人心脏手术中的新型麻醉与复苏技术]

[New anesthetic and resuscitation techniques in adult cardiac surgery].

作者信息

Roediger L, Larbuisson R, Senard M, Hubert B, Damas P, Lamy M

机构信息

Département d'Anesthésie-Réanimation, CHU Sart Tilman, Liège.

出版信息

Rev Med Liege. 2004 Jan;59(1):35-45.

Abstract

Anesthetic techniques and treatment of cardiac surgery patients have considerably evolved over the past twenty years. The demand for cardiac surgical procedures is increasing. This demand coincides with a change in the profile of patients presenting for surgery, requiring modification in perioperative management strategies. Several new anesthetics, related drugs, and technologies have become available in recent years that inevitably have made new approaches with patient management possible. In parallel to these new developments, there have appeared real opportunities to apply novel physiologic and pharmacologic concepts that may redefine our clinical practice. Fast-tracking, which emphasizes the major role of anesthetic management in postoperative outcome, is one such line of investigation. Fast-tracking was first introduced in an attempt to decrease the time to tracheal extubation and reduce expensive time in intensive care unit areas. Large doses of opioids have been clearly identified as a factor in delaying weaning from mechanical ventilatory support after cardiac surgery. Thus, early investigations emphasized the importance of limiting the dose of potent opioid analgesics during the intraoperative period to achieve early recovery. Supplementation with hypnotic drugs allows reduction of the opioid dose, enabling earlier extubation without compromising hemodynamic stability. Fast track cardiac anesthesia (FTCA) is becoming an accepted practice for perioperative management of cardiac surgical patients. FTCA is a key component to successful conduction of fast-track cardiac surgery. Also, analgesia management in cardiac surgery is becoming more important with the establishment of minimally invasive direct coronary artery bypass surgery and fast track management of conventional cardiac surgery patients.

摘要

在过去二十年中,心脏手术患者的麻醉技术和治疗方法有了显著发展。心脏外科手术的需求不断增加。这种需求与接受手术患者的特征变化相吻合,这就需要对围手术期管理策略进行调整。近年来,有几种新型麻醉剂、相关药物和技术问世,这必然使采用新的患者管理方法成为可能。与这些新进展同时出现的是,出现了应用可能重新定义我们临床实践的新生理和药理概念的实际机会。快速康复强调麻醉管理在术后结果中的主要作用,就是这样一种研究方向。快速康复最初是为了缩短气管拔管时间并减少在重症监护病房的昂贵停留时间而引入的。大剂量阿片类药物已被明确认定为心脏手术后延迟脱离机械通气支持的一个因素。因此,早期研究强调了在术中限制强效阿片类镇痛药剂量以实现早期康复的重要性。补充催眠药物可减少阿片类药物剂量,从而能够在不影响血流动力学稳定性的情况下更早拔管。快速康复心脏麻醉(FTCA)正成为心脏手术患者围手术期管理的一种公认做法。FTCA是成功实施快速康复心脏手术的关键组成部分。此外,随着微创直接冠状动脉搭桥手术的开展以及传统心脏手术患者的快速康复管理,心脏手术中的镇痛管理变得更加重要。

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